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NCT07410312 · ClinicalTrials.gov registry record · Early Phase 1

BRIDGE - Blocking Receptor of IL-1β for Donor Graft Edema Reduction

A Early Phase 1 study, sponsored by Northwestern University.

Not yet
Registry status
Early Phase 1
Development phase
20
Enrollment target

NCT07410312 is a Early Phase 1 study that has not yet begun recruiting, run by Northwestern University. The registered enrollment target is 20 participants.

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The verdict

NCT07410312, a Early Phase 1 study, has not yet begun recruiting, sponsored by Northwestern University.

NOT YET RECRUITING
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This study will determine if primary graft dysfunction (which causes low blood oxygen levels and fluid or inflammation in the lungs) after lung transplant can be prevented through the use of the study drug (IL-1 receptor antagonist, Anakinra). In this study, lung transplant participants who are randomized to the treatment group will have the study drug injected into the solution that their donor lungs are kept in prior to transplant.

Interventions

  • DRUG Anakinra

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-07-01
Est. Completion 2027-12
Phase Early Phase 1

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT07410312

The ClinicalTrials.gov registry entry for NCT07410312 describes a study currently listed as not yet recruiting, categorized as Early Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Anakinra is the first listed.

NCT07410312 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07410312 about?

NCT07410312 is a clinical study titled "BRIDGE - Blocking Receptor of IL-1β for Donor Graft Edema Reduction". This study will determine if primary graft dysfunction (which causes low blood oxygen levels and fluid or inflammation in the lungs) after lung transplant can be prevented through the use of the study drug (IL-1 receptor antagonist, Anakinra). In this study, lung transplant participants who are rand...

What is the current status of trial NCT07410312?

This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2026-07-01. Estimated completion is 2027-12.

What interventions are being tested in trial NCT07410312?

The interventions under investigation include: Anakinra (DRUG).

Who is sponsoring clinical trial NCT07410312?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.