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NCT07408258 · ClinicalTrials.gov registry record · Phase 1
Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors
A Phase 1 study, sponsored by OncoC4.
- Not yet
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT07408258: Clinical Trial Phase 1 study, sponsored by OncoC4.
NCT07408258 is a Phase 1 study that has not yet begun recruiting, run by OncoC4. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07408258, a Phase 1 study, has not yet begun recruiting, sponsored by OncoC4.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
ONC-783-001 is a Phase I open label, dose-escalation study for evaluating the safety, pharmacokinetics (PK) and efficacy of ONC-783 as a single agent in patients with advanced/metastatic solid tumors, focusing on colorectal cancer, ovarian cancer, pancreatic cancer, or breast cancer.
Primary Outcome
Recommended Phase 2 dose of the study drug ONC-783
Interventions
- DRUG ONC-783
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-06-01 |
| Est. Completion | 2028-06-01 |
| Phase | Phase 1 |
What is known before NCT07408258 opens enrollment
NCT07408258 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which ONC-783 is the first listed.
NCT07408258 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07408258 about?
NCT07408258 is a clinical study titled "Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors". ONC-783-001 is a Phase I open label, dose-escalation study for evaluating the safety, pharmacokinetics (PK) and efficacy of ONC-783 as a single agent in patients with advanced/metastatic solid tumors, focusing on colorectal cancer, ovarian cancer, pancreatic cancer, or breast cancer.
What is the current status of trial NCT07408258?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2026-06-01. Estimated completion is 2028-06-01.
What interventions are being tested in trial NCT07408258?
The interventions under investigation include: ONC-783 (DRUG).
Who is sponsoring clinical trial NCT07408258?
This trial is sponsored by OncoC4, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07408258's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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