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NCT07406698 · ClinicalTrials.gov registry record · NA
Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis
A NA study of Pancreatitis, Acute Necrotizing, sponsored by Orlando Health.
- Recruiting
- Registry status
- NA
- Development phase
- 104
- Enrollment target
- 1
- Study location
NCT07406698 is a NA study of Pancreatitis, Acute Necrotizing that is actively recruiting participants, run by Orlando Health. The registered enrollment target is 104 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07406698, a NA study of Pancreatitis, Acute Necrotizing, is actively recruiting participants, sponsored by Orlando Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 104 participants
- Enrollment target
- 1
- Study location
Study Summary
Pancreatic necrosis complicates approximately 20-30% of severe acute pancreatitis cases. While many collections resolve without intervention, persistent symptomatic collections-particularly when infected-are associated with significant morbidity and mortality and frequently require procedural management. Current guidelines recommend delaying intervention until collections are fully walled off, typically around four weeks. However, in clinical practice, many patients deteriorate before this window is reached. Prospective data from our institution, supported by recent meta-analyses, suggest that early intervention using modern endoscopic techniques can be performed safely, even when undertaken within the first four weeks of disease onset. We believe that, in appropriately selected patients, early endoscopic intervention may prevent clinical deterioration, reduce complications, shorten hospital stay, and decrease overall healthcare utilization compared with a delayed approach. To formally evaluate this strategy, an international, multicenter randomized trial is being conducted, entitled Strategic Timing of Endoscopic Procedural Interventions in Infected Necrotizing Pancreatitis (STEP-IN Trial).
Conditions Studied
Interventions
- PROCEDURE EUS-guided transluminal drainage of necrotic collection
Study Locations (1)
Florida
- Orlando Health Digestive Health Institute - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2026-01-28 |
| Est. Completion | 2029-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07406698
The ClinicalTrials.gov registry entry for NCT07406698 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 104 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Orlando Health, which has 21 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pancreatitis, Acute Necrotizing appearing as the primary indexed condition, and to 1 intervention - of which EUS-guided transluminal drainage of necrotic collection is the first listed.
NCT07406698 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT07406698 about?
NCT07406698 is a clinical study titled "Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis". Pancreatic necrosis complicates approximately 20-30% of severe acute pancreatitis cases. While many collections resolve without intervention, persistent symptomatic collections-particularly when infected-are associated with significant morbidity and mortality and frequently require procedural manage...
What is the current status of trial NCT07406698?
This trial is currently recruiting. It is a NA study. The enrollment target is 104 participants. The study started on 2026-01-28. Estimated completion is 2029-12-31.
What conditions does trial NCT07406698 study?
This clinical trial studies the following conditions: Pancreatitis, Acute Necrotizing.
What interventions are being tested in trial NCT07406698?
The interventions under investigation include: EUS-guided transluminal drainage of necrotic collection (PROCEDURE).
Who is sponsoring clinical trial NCT07406698?
This trial is sponsored by Orlando Health, which has 21 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07406698 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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