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NCT07406360 · ClinicalTrials.gov registry record · Phase 3

A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age

A Phase 3 study, sponsored by GlaxoSmithKline.

Recruiting
Registry status
Phase 3
Development phase
1,209
Enrollment target

NCT07406360: Recruiting Phase 3 study, sponsored by GlaxoSmithKline.

NCT07406360 is a Phase 3 study that is actively recruiting participants, run by GlaxoSmithKline. The registered enrollment target is 1,209 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07406360, a Phase 3 study, is actively recruiting participants, sponsored by GlaxoSmithKline.

RECRUITING
Registry status
Phase 3
Development phase
1,209 participants
Enrollment target

Study Summary

This study is evaluating the immunogenicity and safety of intramuscular administration of the investigational MMRVNS vaccine compared to intramuscular administration of the MMRV (Merck's measles, mumps, rubella and varicella) vaccine (ProQuad) that is already licensed for this route, when administered as a second dose in children 15 months to 6 years of age who were previously primed with a first dose of any combination of measles, mumps, rubella and varicella-containing vaccine(s).

Interventions

  • BIOLOGICAL MMRVNS
  • BIOLOGICAL MMRV

Trial Details

FieldValue
Enrollment Target 1,209 participants
Start Date 2026-05-11
Est. Completion 2028-07-20
Phase Phase 3
GlaxoSmithKline

1,345 total trials

What NCT07406360 shows while recruiting

NCT07406360 is an interventional study that assigns participants to a tested intervention. Its 1,209 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% higher).

The record links to 0 conditions, and to 2 interventions - of which MMRVNS is the first listed.

NCT07406360 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07406360 about?

NCT07406360 is a clinical study titled "A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age". This study is evaluating the immunogenicity and safety of intramuscular administration of the investigational MMRVNS vaccine compared to intramuscular administration of the MMRV (Merck's measles, mumps, rubella and varicella) vaccine (ProQuad) that is already licensed for this route, when administer...

What is the current status of trial NCT07406360?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,209 participants. The study started on 2026-05-11. Estimated completion is 2028-07-20.

What interventions are being tested in trial NCT07406360?

The interventions under investigation include: MMRVNS (BIOLOGICAL), MMRV (BIOLOGICAL).

Who is sponsoring clinical trial NCT07406360?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07406360's enrollment target sits among peer trials

1,209 217th of 2000 higher than 1,783 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07406360, the US trial registry maintained by the National Library of Medicine. NCT07406360 (large enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.