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NCT07398989 · ClinicalTrials.gov registry record · Phase 4
A Clinical Study to Assess Efficacy and Tolerability of a Topical Skincare Product on Adults With Mature, Crepey Skin
A Phase 4 study of Photo-aged Skin and Crepey Skin, sponsored by Galderma R&D.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
- 2
- Study locations
NCT07398989: Recruiting Phase 4 study of Photo-aged Skin and Crepey Skin, sponsored by Galderma R&D.
NCT07398989 is a Phase 4 study of Photo-aged Skin and Crepey Skin that is actively recruiting participants, run by Galderma R&D. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07398989, a Phase 4 study of Photo-aged Skin and Crepey Skin, is actively recruiting participants, sponsored by Galderma R&D.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
- 2
- Study locations
Study Summary
Subjects having mild-to-moderate crepiness, photodamage, and loss of firmness will apply a topical skincare regimen to the knees, thighs, hands, and all over the body. Evaluations of the regimen's efficacy will be conducted at 4 weeks, 8 weeks, and 12 weeks post-baseline.
Primary Outcome
Clinical grading of efficacy parameters will be performed at both study sites. The efficacy parameters will be assessed by the Investigators at the knees and lower thighs using a modified Griffiths' 10-point scale , with 0 indicating best possible condition and 9 indicating worst possible condition. Half-point scores may be used as necessary to more accurately describe the skin condition. A decrease in scores indicates an improvement.
Conditions Studied
Interventions
- DRUG Cetaphil
Study Locations (2)
California
- Ablon Skin Institute & Research Center - Manhattan Beach
South Carolina
- Clinical Research Center of the Carolinas - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-08-12 |
| Est. Completion | 2026-03 |
| Phase | Phase 4 |
What NCT07398989 shows while recruiting
NCT07398989 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 3 conditions, with Photo-aged Skin appearing as the primary indexed condition, and to 1 intervention - of which Cetaphil is the first listed.
NCT07398989 reports a single indexed study location in California, South Carolina.
Frequently Asked Questions
What is clinical trial NCT07398989 about?
NCT07398989 is a clinical study titled "A Clinical Study to Assess Efficacy and Tolerability of a Topical Skincare Product on Adults With Mature, Crepey Skin". Subjects having mild-to-moderate crepiness, photodamage, and loss of firmness will apply a topical skincare regimen to the knees, thighs, hands, and all over the body. Evaluations of the regimen's efficacy will be conducted at 4 weeks, 8 weeks, and 12 weeks post-baseline.
What is the current status of trial NCT07398989?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2025-08-12. Estimated completion is 2026-03.
What conditions does trial NCT07398989 study?
This clinical trial studies the following conditions: Photo-aged Skin, Crepey Skin, Aging Skin.
What interventions are being tested in trial NCT07398989?
The interventions under investigation include: Cetaphil (DRUG).
Who is sponsoring clinical trial NCT07398989?
This trial is sponsored by Galderma R&D, which has 158 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07398989 being conducted?
This trial has 2 study locations across California, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Photo-aged Skin
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07398989's enrollment target sits among peer trials
30 1552nd of 2000 higher than 368 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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