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NCT07398157 · ClinicalTrials.gov registry record · NA

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

A NA study, sponsored by University of California, San Francisco.

Recruiting
Registry status
NA
Development phase
24
Enrollment target

NCT07398157: Recruiting NA study, sponsored by University of California, San Francisco.

NCT07398157 is a NA study that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07398157, a NA study, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
NA
Development phase
24 participants
Enrollment target

Study Summary

The purpose of this study is to test a new way to treat Parkinson's disease (PD). Subjects will be implanted with deep brain stimulator (DBS) devices and electrodes placed under the scalp. The main questions it aims to answer are: * Is there a less invasive method to collect useful brain signals? Find out if these brain signals can be related to movement and/or sleep symptoms. * How to use these brain signals to tailor adaptive deep brain stimulation settings for movement and/or sleep symptoms Researchers will compare study derived adaptive DBS settings to subject's clinically programmed continuous DBS settings to see which is better at treating patients PD symptoms.

Primary Outcome

Troublesome movement and/or sleep episodes will be detected using validated home wearable devices along with participant self-reporting.

Interventions

  • DEVICE Medtronic Percept Deep Brain Stimulation (cDBS)
  • DEVICE Medtronic Percept Deep Brain Stimulation (daytime aDBS)
  • DEVICE Medtronic Percept Deep Brain Stimulation (nighttime aDBS)

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2026-04-09
Est. Completion 2031-11-30
Phase NA

What NCT07398157 shows while recruiting

NCT07398157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which Medtronic Percept Deep Brain Stimulation (cDBS) is the first listed.

NCT07398157 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07398157 about?

NCT07398157 is a clinical study titled "Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease". The purpose of this study is to test a new way to treat Parkinson's disease (PD). Subjects will be implanted with deep brain stimulator (DBS) devices and electrodes placed under the scalp. The main questions it aims to answer are: * Is there a less invasive method to collect useful brain signals? ...

What is the current status of trial NCT07398157?

This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2026-04-09. Estimated completion is 2031-11-30.

What interventions are being tested in trial NCT07398157?

The interventions under investigation include: Medtronic Percept Deep Brain Stimulation (cDBS) (DEVICE), Medtronic Percept Deep Brain Stimulation (daytime aDBS) (DEVICE), Medtronic Percept Deep Brain Stimulation (nighttime aDBS) (DEVICE).

Who is sponsoring clinical trial NCT07398157?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07398157's enrollment target sits among peer trials

24 1736th of 2000 higher than 246 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07398157, the US trial registry maintained by the National Library of Medicine. NCT07398157 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.