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NCT07396584 · ClinicalTrials.gov registry record · Phase 1
HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor
A Phase 1 study, sponsored by Hutchmed.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 186
- Enrollment target
NCT07396584: Recruiting Phase 1 study, sponsored by Hutchmed.
NCT07396584 is a Phase 1 study that is actively recruiting participants, run by Hutchmed. The registered enrollment target is 186 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (210% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07396584, a Phase 1 study, is actively recruiting participants, sponsored by Hutchmed.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 186 participants
- Enrollment target
Study Summary
This is a first-in-human, multicenter, open-label, phase I/Ⅱa clinical study of HMPL-A580 in participants with unresectable, advanced or metastatic solid tumors.
Primary Outcome
To evaluate the safety, tolerability, and MTD) and/or RDE of HMPL-A580 in solid tumors
Interventions
- DRUG HMPL-A580
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 186 participants |
| Start Date | 2026-03-04 |
| Est. Completion | 2029-01-30 |
| Phase | Phase 1 |
What NCT07396584 shows while recruiting
NCT07396584 is an interventional study that assigns participants to a tested intervention. The registered 186 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (210% higher).
The record links to 0 conditions, and to 1 intervention - of which HMPL-A580 is the first listed.
NCT07396584 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07396584 about?
NCT07396584 is a clinical study titled "HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor". This is a first-in-human, multicenter, open-label, phase I/Ⅱa clinical study of HMPL-A580 in participants with unresectable, advanced or metastatic solid tumors.
What is the current status of trial NCT07396584?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 186 participants. The study started on 2026-03-04. Estimated completion is 2029-01-30.
What interventions are being tested in trial NCT07396584?
The interventions under investigation include: HMPL-A580 (DRUG).
Who is sponsoring clinical trial NCT07396584?
This trial is sponsored by Hutchmed, which has 17 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07396584's enrollment target sits among peer trials
186 291st of 2000 higher than 1,707 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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