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NCT07386509 · ClinicalTrials.gov registry record · Early Phase 1

WU 345: Immune Responses to Adjuvanted and Non-adjuvanted Seasonal Influenza Vaccines in the Lymphoid Tissues.

A Early Phase 1 study, sponsored by Washington University School of Medicine.

Terminated
Registry status
Early Phase 1
Development phase
2
Enrollment target

NCT07386509: Clinical Trial Early Phase 1 study, sponsored by Washington University School of Medicine.

NCT07386509 is a Early Phase 1 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 2 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07386509, a Early Phase 1 study, was terminated before completion, sponsored by Washington University School of Medicine.

TERMINATED
Registry status
Early Phase 1
Development phase
2 participants
Enrollment target

Study Summary

Healthy adults (18-49 years of age) with no previous influenza virus vaccination history for at least three years prior to enrollment will be recruited to participate in this study. All subjects will concomitantly receive a single dose of both Fluad® and Afluria® administered intramuscularly in opposite deltoid muscles. Blood samples collected at 9 visits (screening, baseline, days 7, 14, 28, 60, 90, 120 and 180, fine needle aspiration (FNAs) from axillary lymph nodes from both axillae at baseline, days 7, 14, 28, 60, 90, 120 and 180.

Interventions

  • DRUG Fluad® and Afluria® vaccination

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2020-03-17
Est. Completion 2022-11-04
Phase Early Phase 1

Why NCT07386509 stopped before completion

NCT07386509 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which Fluad® and Afluria® vaccination is the first listed.

NCT07386509 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07386509 about?

NCT07386509 is a clinical study titled "WU 345: Immune Responses to Adjuvanted and Non-adjuvanted Seasonal Influenza Vaccines in the Lymphoid Tissues.". Healthy adults (18-49 years of age) with no previous influenza virus vaccination history for at least three years prior to enrollment will be recruited to participate in this study. All subjects will concomitantly receive a single dose of both Fluad® and Afluria® administered intramuscularly in oppo...

What is the current status of trial NCT07386509?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 2 participants. The study started on 2020-03-17. Estimated completion is 2022-11-04.

What interventions are being tested in trial NCT07386509?

The interventions under investigation include: Fluad® and Afluria® vaccination (DRUG).

Who is sponsoring clinical trial NCT07386509?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07386509's enrollment target sits among peer trials

2 1973rd of 2000 higher than 16 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07386509, the US trial registry maintained by the National Library of Medicine. NCT07386509 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.