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NCT07358546 · ClinicalTrials.gov registry record · Phase 1

A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

A Phase 1 study, sponsored by GlaxoSmithKline.

Recruiting
Registry status
Phase 1
Development phase
32
Enrollment target

NCT07358546 is a Phase 1 study that is actively recruiting participants, run by GlaxoSmithKline. The registered enrollment target is 32 participants.

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The verdict

NCT07358546, a Phase 1 study, is actively recruiting participants, sponsored by GlaxoSmithKline.

RECRUITING
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

This study is designed to study the pharmacokinetic (PK) and safety profiles of a single dose of efimosfermin alfa in participants with varying degrees of Hepatic Impairment (HI) (assessed by Child-Pugh score) due to steatotic liver disease, with and without significant alcohol consumption.

Interventions

  • DRUG Efimosfermin alfa

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2026-03-13
Est. Completion 2027-10-13
Phase Phase 1

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT07358546

The ClinicalTrials.gov registry entry for NCT07358546 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Efimosfermin alfa is the first listed.

NCT07358546 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07358546 about?

NCT07358546 is a clinical study titled "A Study of Efimosfermin Alfa in Adults With Hepatic Impairment". This study is designed to study the pharmacokinetic (PK) and safety profiles of a single dose of efimosfermin alfa in participants with varying degrees of Hepatic Impairment (HI) (assessed by Child-Pugh score) due to steatotic liver disease, with and without significant alcohol consumption.

What is the current status of trial NCT07358546?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2026-03-13. Estimated completion is 2027-10-13.

What interventions are being tested in trial NCT07358546?

The interventions under investigation include: Efimosfermin alfa (DRUG).

Who is sponsoring clinical trial NCT07358546?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.