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NCT07356635 · ClinicalTrials.gov registry record · NA
Cardiovascular Effects of Grieving
A NA study of Cardiovascular Health and Grief, sponsored by University of South Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT07356635: Recruiting NA study of Cardiovascular Health and Grief, sponsored by University of South Florida.
NCT07356635 is a NA study of Cardiovascular Health and Grief that is actively recruiting participants, run by University of South Florida. The registered enrollment target is 140 participants, below the 154,442-participant average among 13 other Cardiovascular Health trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07356635, a NA study of Cardiovascular Health and Grief, is actively recruiting participants, sponsored by University of South Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular recovery in response to stress. While SA is discussed as a way to alleviate grief, its effect on cardiovascular reactivity (CVR) and recovery to grief recall has yet to be studied within laboratory settings. This study proposes an experimental design to examine how an in-lab manipulation promoting self-affirmation can improve patients' cardiovascular responses during and after a grief recall procedure. The investigators hypothesized that grief severity (a continuous variable) interacts with condition (a categorical variable with two levels, i.e., SA intervention vs. control) to predict CV reactivity and recovery as outcomes. Primary Objective 1: To investigate effects of self-affirmation intervention on cardiovascular responses among grieving participants during and after grief recall. Secondary Objective 1: To investigate the relationship of grief severity with psychological stress.
Primary Outcome
A series of one-way ANCOVAs will be conducted to compare measures of cardiovascular reactivity and recovery between the self-affirmation and control conditions, controlling for gender, race, and baseline values, using a significance level of α = .05. CV reactivity will be operationalized as the difference between CV during grief recall and CV baseline measures. CV recovery will be operationalized as the difference between CV recovery measures and CV baseline measures.
Conditions Studied
Interventions
- BEHAVIORAL Value-affirmation
Study Locations (1)
Florida
- University of South Florida, Psychology and Communication Sciences and Disorders Lab Building - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2025-10-16 |
| Est. Completion | 2027-03 |
| Phase | NA |
What NCT07356635 shows while recruiting
NCT07356635 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 154,442-participant average among 13 other Cardiovascular Health trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Cardiovascular Health appearing as the primary indexed condition, and to 1 intervention - of which Value-affirmation is the first listed.
NCT07356635 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT07356635 about?
NCT07356635 is a clinical study titled "Cardiovascular Effects of Grieving". Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular re...
What is the current status of trial NCT07356635?
This trial is currently recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2025-10-16. Estimated completion is 2027-03.
What conditions does trial NCT07356635 study?
This clinical trial studies the following conditions: Cardiovascular Health, Grief, Emotion.
What interventions are being tested in trial NCT07356635?
The interventions under investigation include: Value-affirmation (BEHAVIORAL).
Who is sponsoring clinical trial NCT07356635?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07356635 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Health
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07356635's enrollment target sits among peer trials
140 5th of 13 higher than 9 of 13 other Cardiovascular Health trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Health trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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