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NCT07336368 · ClinicalTrials.gov registry record · Phase 3

Topical Cryotherapy and Keloid/Hypertrophic Scars

A Phase 3 study of Keloid Scars and Hypertrophic Scars, sponsored by Sonal Choudhary.

Recruiting
Registry status
Phase 3
Development phase
30
Enrollment target
1
Study location

NCT07336368: Recruiting Phase 3 study of Keloid Scars and Hypertrophic Scars, sponsored by Sonal Choudhary.

NCT07336368 is a Phase 3 study of Keloid Scars and Hypertrophic Scars that is actively recruiting participants, run by Sonal Choudhary. The registered enrollment target is 30 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07336368, a Phase 3 study of Keloid Scars and Hypertrophic Scars, is actively recruiting participants, sponsored by Sonal Choudhary.

RECRUITING
Registry status
Phase 3
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.

Primary Outcome

Pain perception during intralesional corticosteroid injection will be assessed using a patient-reported numeric rating scale (0 = No pain, 10 = Very severe pain).

Interventions

  • DEVICE Cryotherapy with liquid nitrogen
  • DRUG Intralesional Triamcinolone 10 mg/ml

Study Locations (1)

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2026-03
Est. Completion 2026-08
Phase Phase 3
Sonal Choudhary

1 total trials

What NCT07336368 shows while recruiting

NCT07336368 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower).

The record links to 2 conditions, with Keloid Scars appearing as the primary indexed condition, and to 2 interventions - of which Cryotherapy with liquid nitrogen is the first listed.

NCT07336368 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT07336368 about?

NCT07336368 is a clinical study titled "Topical Cryotherapy and Keloid/Hypertrophic Scars". The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it...

What is the current status of trial NCT07336368?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2026-03. Estimated completion is 2026-08.

What conditions does trial NCT07336368 study?

This clinical trial studies the following conditions: Keloid Scars, Hypertrophic Scars.

What interventions are being tested in trial NCT07336368?

The interventions under investigation include: Cryotherapy with liquid nitrogen (DEVICE), Intralesional Triamcinolone 10 mg/ml (DRUG).

Who is sponsoring clinical trial NCT07336368?

This trial is sponsored by Sonal Choudhary, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07336368 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT07336368's enrollment target sits among peer trials

30 1918th of 2000 higher than 68 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07336368, the US trial registry maintained by the National Library of Medicine. NCT07336368 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.