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RECRUITING Phase 2

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

NCT07332000 · View on ClinicalTrials.gov ↗

Study Summary

Phase 2a, open-label, multi-center study evaluating biomarkers and biodistribution of aglatimagene besadenovec plus valacyclovir in men with localized, intermediate-risk prostate cancer who are planning to receive external beam radiation therapy (EBRT).

Interventions

  • BIOLOGICAL aglatimagene besadenovec + valacyclovir
  • RADIATION External Beam Radiation Therapy (EBRT)

Study Locations (7)

Colorado

  • Colorado Clinical Research — Lakewood
  • Urology Associates — Littleton

Arizona

  • Academic Urology and Urogynecology of Arizona — Peoria

Maryland

  • Chesapeake Urology Research Associates — Towson

Nevada

  • Sheldon Freedman, MD Ltd. — Las Vegas

New Jersey

  • Summit Health — Saddle Brook

South Carolina

  • START Carolinas — Myrtle Beach

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-10-30
Est. Completion 2026-08
Phase Phase 2

Sponsor

Candel Therapeutics

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07332000

The ClinicalTrials.gov registry entry for NCT07332000 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Candel Therapeutics, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Prostate Cancer (Adenocarcinoma) appearing as the primary indexed condition, and to 2 interventions — of which aglatimagene besadenovec + valacyclovir is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07332000 reports 7 study locations spanning 6 distinct geographic areas — top geographies include Colorado, Arizona, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07332000 about?

NCT07332000 is a clinical study titled "A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec". Phase 2a, open-label, multi-center study evaluating biomarkers and biodistribution of aglatimagene besadenovec plus valacyclovir in men with localized, intermediate-risk prostate cancer who are planning to receive external beam radiation therapy (EBRT).

What is the current status of trial NCT07332000?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2025-10-30. Estimated completion is 2026-08.

What conditions does trial NCT07332000 study?

This clinical trial studies the following conditions: Prostate Cancer (Adenocarcinoma), Prostate Cancer Patients Treated by Radiotherapy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07332000?

The interventions under investigation include: aglatimagene besadenovec + valacyclovir (BIOLOGICAL), External Beam Radiation Therapy (EBRT) (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07332000?

This trial is sponsored by Candel Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07332000 being conducted?

This trial has 7 study locations across Arizona, Colorado, Maryland, Nevada, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial