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NCT07329153 · ClinicalTrials.gov registry record · NA
Neuronavigated aiTBS for TRD
A NA study, sponsored by University of Texas Southwestern Medical Center.
- Not yet
- Registry status
- NA
- Development phase
- 247
- Enrollment target
NCT07329153: Clinical Trial NA study, sponsored by University of Texas Southwestern Medical Center.
NCT07329153 is a NA study that has not yet begun recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 247 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07329153, a NA study, has not yet begun recruiting, sponsored by University of Texas Southwestern Medical Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 247 participants
- Enrollment target
Study Summary
The purpose of this study is to confirm the efficacy of two recently introduced repetitive transcranial magnetic stimulation (rTMS) interventions - accelerated intermittent theta-burst stimulation (aiTBS) and individualized neuronavigation - in treatment-resistant depression (TRD). Using a three-arm design (neuronavigated aiTBS, non-neuronavigated aiTBS, and sham), this randomized controlled trial (RCT) is the first to specifically investigate the incremental benefit of neuronavigation within an accelerated stimulation protocol, as well as the first confirmatory RCT comparing the efficacy of each of these active treatments vs. sham, overcoming previous generalizability issues and being conducted in an independent, multicenter US TRD sample.
Primary Outcome
depression severity as assessed by the Hamilton Depression Rating Scale-17 items (HDRS-17)
Interventions
- DEVICE aiTBS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 247 participants |
| Start Date | 2026-07 |
| Est. Completion | 2031-09 |
| Phase | NA |
What is known before NCT07329153 opens enrollment
NCT07329153 is an interventional study that assigns participants to a tested intervention. The registered 247 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 1 intervention - of which aiTBS is the first listed.
NCT07329153 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07329153 about?
NCT07329153 is a clinical study titled "Neuronavigated aiTBS for TRD". The purpose of this study is to confirm the efficacy of two recently introduced repetitive transcranial magnetic stimulation (rTMS) interventions - accelerated intermittent theta-burst stimulation (aiTBS) and individualized neuronavigation - in treatment-resistant depression (TRD). Using a three-arm...
What is the current status of trial NCT07329153?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 247 participants. The study started on 2026-07. Estimated completion is 2031-09.
What interventions are being tested in trial NCT07329153?
The interventions under investigation include: aiTBS (DEVICE).
Who is sponsoring clinical trial NCT07329153?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07329153's enrollment target sits among peer trials
247 436th of 2000 higher than 1,565 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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