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NCT07325513 · ClinicalTrials.gov registry record · NA
Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain
A NA study, sponsored by Veterans Medical Research Foundation.
- Recruiting
- Registry status
- NA
- Development phase
- 140
- Enrollment target
NCT07325513: Recruiting NA study, sponsored by Veterans Medical Research Foundation.
NCT07325513 is a NA study that is actively recruiting participants, run by Veterans Medical Research Foundation. The registered enrollment target is 140 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07325513, a NA study, is actively recruiting participants, sponsored by Veterans Medical Research Foundation.
- RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to create a machine learning algorithm to improve active repetitive transcranial magnetic stimulation (rTMS) treatments for veterans and/or active military personnel by alleviating Gulf War Illness related headaches and body pain (GWI-HAP). This study aims to develop and validate a Support Vector Machine (SVM) model that could replace the trial-and-error process by assessing functional connectivity provided by resting state functional magnetic resonance imaging (rs-fMRI) data to predict the most effective rTMS protocol for each person. All participants will be receiving active rTMS treatment. The main questions it intends to answer are: 1. Does the SVM model predict a more effective treatment response rate for predicted respondents undergoing active rTMS at the left dorsolateral prefrontal cortex (DLPFC) compared to predicted non-respondents? 2. Does the SVM model predict a more effective treatment response rate while undergoing active rTMS at the left dorsolateral prefrontal cortex (DLPFC) and left motor cortex (LMC) in predicted respondents compared to predicted non-respondents? Participants will undergo the following: 1. Receive a total of 13 active rTMS treatment sessions over 3-4 months. 2. Visit the clinic for a total of 15 visits for assessments, check ups, and treatments. 3. Keep a daily log of their headaches, muscle and joint pain throughout the study.
Primary Outcome
A scale that ranges from 0 to 10 ("No pain" to "Worst possible pain").
Interventions
- DEVICE Active Repetitive Transcranial Magnetic Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2026-03-25 |
| Est. Completion | 2029-10 |
| Phase | NA |
What NCT07325513 shows while recruiting
NCT07325513 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which Active Repetitive Transcranial Magnetic Stimulation is the first listed.
NCT07325513 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07325513 about?
NCT07325513 is a clinical study titled "Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain". The goal of this clinical trial is to create a machine learning algorithm to improve active repetitive transcranial magnetic stimulation (rTMS) treatments for veterans and/or active military personnel by alleviating Gulf War Illness related headaches and body pain (GWI-HAP). This study aims to devel...
What is the current status of trial NCT07325513?
This trial is currently recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2026-03-25. Estimated completion is 2029-10.
What interventions are being tested in trial NCT07325513?
The interventions under investigation include: Active Repetitive Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07325513?
This trial is sponsored by Veterans Medical Research Foundation, which has 35 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07325513's enrollment target sits among peer trials
140 713th of 2000 higher than 1,281 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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