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NCT07325487 · ClinicalTrials.gov registry record · NA
Interposed Nucleus aDBS for Ataxia
A NA study, sponsored by University of Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT07325487 is a NA study that is actively recruiting participants, run by University of Florida. The registered enrollment target is 5 participants.
The verdict
NCT07325487, a NA study, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
This is a single-center, open-label study designed to evaluate the feasibility, safety, and preliminary efficacy of cerebellar adaptive deep brain stimulation (aDBS) in adults with spinocerebellar ataxia type 6 (SCA6). A total of 5 participants will be enrolled. Participants will undergo surgical implantation of deep brain stimulation (DBS) leads targeting the motor interposed nucleus of the cerebellum. The leads will be connected to one or two implantable pulse generators capable of delivering stimulation to deep brain structures and recording neural activity. Participants will complete up to 18 in-person study visits over a 24-month follow-up period. During these visits, neural signals will be recorded under varying behavioral tasks and stimulation conditions. Early study visits will be used to identify optimal stimulation parameters and neural biomarkers associated with disease state. These biomarkers will subsequently be used to implement adaptive DBS, in which stimulation amplitude is automatically adjusted in response to recorded neural activity. Study outcomes will include assessments of safety and feasibility of cerebellar aDBS, as well as preliminary evaluation of its effects on clinical measures.
Interventions
- DEVICE Deep Brain Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2026-06-02 |
| Est. Completion | 2031-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07325487
The ClinicalTrials.gov registry entry for NCT07325487 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Deep Brain Stimulation is the first listed.
NCT07325487 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07325487 about?
NCT07325487 is a clinical study titled "Interposed Nucleus aDBS for Ataxia". This is a single-center, open-label study designed to evaluate the feasibility, safety, and preliminary efficacy of cerebellar adaptive deep brain stimulation (aDBS) in adults with spinocerebellar ataxia type 6 (SCA6). A total of 5 participants will be enrolled. Participants will undergo surgical i...
What is the current status of trial NCT07325487?
This trial is currently recruiting. It is a NA study. The enrollment target is 5 participants. The study started on 2026-06-02. Estimated completion is 2031-06.
What interventions are being tested in trial NCT07325487?
The interventions under investigation include: Deep Brain Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07325487?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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