Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07321704 · ClinicalTrials.gov registry record · NA
Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease
A NA study of Pilonidal Disease, sponsored by Yosef Nasseri, MD.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT07321704: Recruiting NA study of Pilonidal Disease, sponsored by Yosef Nasseri, MD.
NCT07321704 is a NA study of Pilonidal Disease that is actively recruiting participants, run by Yosef Nasseri, MD. The registered enrollment target is 60 participants, below the 137-participant average among 5 other Pilonidal Disease trials with a reported enrollment target (56% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07321704, a NA study of Pilonidal Disease, is actively recruiting participants, sponsored by Yosef Nasseri, MD.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Pilonidal disease is a chronic condition that causes painful inflammation and infection near the top of the buttocks. Many patients require surgery, and one commonly used approach is a bilateral gluteal fasciocutaneous flap with midline closure along with placement of an extracellular matrix to support wound healing. Although effective, this surgery can still lead to wound problems such as infection, fluid collection (seroma), wound separation (dehiscence), and delayed healing. This study aims to compare two different solutions used to rinse the surgical wound before closing it. One solution is Irrisept, which contains 0.05% chlorhexidine gluconate, an antiseptic designed to reduce bacteria. The other is normal saline, which is the current standard rinse used in surgery. The goal is to determine whether using Irrisept can safely reduce post-operative infections and wound-related complications in patients undergoing flap closure and extracellular matrix implantation for pilonidal disease.
Primary Outcome
Proportion of participants who experience any treatment-emergent adverse event following surgery and throughout the follow-up period. Adverse events include any unfavorable or unintended sign, symptom, or medical occurrence temporally associated with the study intervention.
Conditions Studied
Interventions
- OTHER Normal Saline
- DEVICE Irrisept (0.05% chlorhexidine gluconate)
Study Locations (1)
California
- Surgery Group LA - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-01-12 |
| Est. Completion | 2027-12-01 |
| Phase | NA |
What NCT07321704 shows while recruiting
NCT07321704 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 137-participant average among 5 other Pilonidal Disease trials with a reported enrollment target (56% lower).
The record links to 1 condition, with Pilonidal Disease appearing as the primary indexed condition, and to 2 interventions - of which Normal Saline is the first listed.
NCT07321704 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07321704 about?
NCT07321704 is a clinical study titled "Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease". Pilonidal disease is a chronic condition that causes painful inflammation and infection near the top of the buttocks. Many patients require surgery, and one commonly used approach is a bilateral gluteal fasciocutaneous flap with midline closure along with placement of an extracellular matrix to supp...
What is the current status of trial NCT07321704?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2026-01-12. Estimated completion is 2027-12-01.
What conditions does trial NCT07321704 study?
This clinical trial studies the following conditions: Pilonidal Disease.
What interventions are being tested in trial NCT07321704?
The interventions under investigation include: Normal Saline (OTHER), Irrisept (0.05% chlorhexidine gluconate) (DEVICE).
Who is sponsoring clinical trial NCT07321704?
This trial is sponsored by Yosef Nasseri, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07321704 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pilonidal Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Pilot Trial Assessing the Effectiveness of Laser Hair Depilation on Pilonidal Disease Recurrence in Patients With Darker Skin Color
RECRUITING · NA
-
Comparing Operative vs Non Operative Treatment for Pilonidal Disease
RECRUITING · NA
-
Laser Hair Removal for Treatment of Pilonidal Disease
COMPLETED · NA
-
Topical Anti-Androgens in Pilonidal Sinus Disease
RECRUITING · Phase 2
-
MIPE for Pilonidal Disease
ACTIVE NOT RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00576069 · 60 participants
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
- NCT01297400 · 60 participants · Phase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- NCT01734122 · 60 participants
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
- NCT01804634 · 60 participants · Phase 2
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI