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NCT07298863 · ClinicalTrials.gov registry record · NA
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
A NA study of Hydration Status and Substrate Metabolism During Exercise, sponsored by PepsiCo Global R&D.
- Recruiting
- Registry status
- NA
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT07298863 is a NA study of Hydration Status and Substrate Metabolism During Exercise that is actively recruiting participants, run by PepsiCo Global R&D. The registered enrollment target is 74 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07298863, a NA study of Hydration Status and Substrate Metabolism During Exercise, is actively recruiting participants, sponsored by PepsiCo Global R&D.
- RECRUITING
- Registry status
- NA
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise). Impairments in metabolic flexibility, also known as metabolic inflexibility, have been suggested to be an underlying cause of metabolic disease, like type 2 diabetes. Long-term low fluid intake may increase the risk of type 2 diabetes due to insulin resistance, a form of metabolic inflexibility. Further, low fluid intake has been shown to impair the ability to switch fuel preference during exercise. While there is some evidence that low fluid intake may lead to impaired metabolic flexibility, more information is needed. Therefore, the purpose of this study is to evaluate the impact of hydration status on substrate preference at rest and during exercise at varying intensities (light and moderate). Further, we will examine whether biological sex and menstrual cycle phase impact hydration and metabolism under these same conditions.
Conditions Studied
Interventions
- OTHER Exercise Trial
- OTHER Experimental Trial
Study Locations (1)
New York
- Gatorade Sports Science Institute - Valhalla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2025-11-05 |
| Est. Completion | 2026-04-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07298863
The ClinicalTrials.gov registry entry for NCT07298863 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is PepsiCo Global R&D, which has 47 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hydration Status appearing as the primary indexed condition, and to 2 interventions - of which Exercise Trial is the first listed.
NCT07298863 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT07298863 about?
NCT07298863 is a clinical study titled "The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise". Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise). Impairments in metabolic flexibility, also known as metabolic inflexibility, have been suggested to be an underlying cause of metabolic ...
What is the current status of trial NCT07298863?
This trial is currently recruiting. It is a NA study. The enrollment target is 74 participants. The study started on 2025-11-05. Estimated completion is 2026-04-30.
What conditions does trial NCT07298863 study?
This clinical trial studies the following conditions: Hydration Status, Substrate Metabolism During Exercise.
What interventions are being tested in trial NCT07298863?
The interventions under investigation include: Exercise Trial (OTHER), Experimental Trial (OTHER).
Who is sponsoring clinical trial NCT07298863?
This trial is sponsored by PepsiCo Global R&D, which has 47 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07298863 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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