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NCT07298460 · ClinicalTrials.gov registry record · Phase 1
Stimulation-based Therapy to Improve Balance in DCM
A Phase 1 study, sponsored by Medical College of Wisconsin.
- Not yet
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
NCT07298460: Clinical Trial Phase 1 study, sponsored by Medical College of Wisconsin.
NCT07298460 is a Phase 1 study that has not yet begun recruiting, run by Medical College of Wisconsin. The registered enrollment target is 45 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07298460, a Phase 1 study, has not yet begun recruiting, sponsored by Medical College of Wisconsin.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to determine if a treatment called transcutaneous spinal cord stimulation (tSCS), when combined with balance training, can help improve balance in adults who have had surgery for degenerative cervical myelopathy (DCM). DCM is a condition that affects the spinal cord in the neck and often causes problems with walking and balance, even after surgery. This study will also look at how tSCS affects the nervous system and whether it is safe and practical to use in this group of patients. The results will help researchers plan a larger study in the future. Main Questions: * Does tSCS combined with balance training improve balance more than balance training alone? * Does stimulation at both the neck and mid-back work better than stimulation at the mid-back only? * What changes in nerve and muscle activity occur with tSCS? What will happen in this study: * Participants will be randomly assigned to one of three groups: 1. tSCS applied to the mid-back (thoracic area) plus balance training 2. tSCS applied to both the neck and mid-back (combined stimulation) plus balance training 3. Sham stimulation (electrodes placed but no stimulation) plus balance training * All participants will complete 12 sessions over 4 weeks (3 sessions per week). * Each session will include 30 minutes of balance training and 30 minutes of walking exercises. * Participants will receive stimulation or sham treatment during these sessions. * Balance and walking tests will be done before and after the program. * Nerve and muscle activity will also be measured at the same time points. This pilot study will help determine if tSCS is effective and safe, and will provide information needed to design a larger trial.
Primary Outcome
The Berg Balance Scale is a validated clinical measure of static and dynamic balance.
Interventions
- DEVICE Transcutaneous spinal cord stimulation
- OTHER Balance and Gait Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2028-07-01 |
| Phase | Phase 1 |
What is known before NCT07298460 opens enrollment
NCT07298460 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 2 interventions - of which Transcutaneous spinal cord stimulation is the first listed.
NCT07298460 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07298460 about?
NCT07298460 is a clinical study titled "Stimulation-based Therapy to Improve Balance in DCM". The goal of this clinical trial is to determine if a treatment called transcutaneous spinal cord stimulation (tSCS), when combined with balance training, can help improve balance in adults who have had surgery for degenerative cervical myelopathy (DCM). DCM is a condition that affects the spinal cor...
What is the current status of trial NCT07298460?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2026-07-01. Estimated completion is 2028-07-01.
What interventions are being tested in trial NCT07298460?
The interventions under investigation include: Transcutaneous spinal cord stimulation (DEVICE), Balance and Gait Training (OTHER).
Who is sponsoring clinical trial NCT07298460?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07298460's enrollment target sits among peer trials
45 1066th of 2000 higher than 915 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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