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NCT07298057 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics
A Early Phase 1 study of Periodontitis, Diabetes Mellitus Type 2, sponsored by Case Western Reserve University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 42
- Enrollment target
- 1
- Study location
NCT07298057 is a Early Phase 1 study of Periodontitis, Diabetes Mellitus Type 2 that is actively recruiting participants, run by Case Western Reserve University. The registered enrollment target is 42 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07298057, a Early Phase 1 study of Periodontitis, Diabetes Mellitus Type 2, is actively recruiting participants, sponsored by Case Western Reserve University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
Periodontitis is a prevalent chronic inflammatory disease that exacerbates systemic inflammation and poses challenges for glycemic control in diabetic patients. While scaling and root planing (SRP) remains the cornerstone of periodontal therapy, adjunctive treatments such as Arestin (minocycline microspheres) have shown promise in enhancing clinical outcomes. This study aims to evaluate the impact of adding Arestin to SRP on periodontal pocket closure, glycemic control, and systemic inflammation in diabetic patients with periodontitis.
Conditions Studied
Interventions
- DRUG local antibiotic application of topical minocycline
- PROCEDURE Scaling and Root Planing
Study Locations (1)
Ohio
- Case Western Reserve University - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2026-02-06 |
| Est. Completion | 2028-06 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07298057
The ClinicalTrials.gov registry entry for NCT07298057 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Case Western Reserve University, which has 141 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Periodontitis, Diabetes Mellitus Type 2 appearing as the primary indexed condition, and to 2 interventions - of which local antibiotic application of topical minocycline is the first listed.
NCT07298057 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT07298057 about?
NCT07298057 is a clinical study titled "Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics". Periodontitis is a prevalent chronic inflammatory disease that exacerbates systemic inflammation and poses challenges for glycemic control in diabetic patients. While scaling and root planing (SRP) remains the cornerstone of periodontal therapy, adjunctive treatments such as Arestin (minocycline mic...
What is the current status of trial NCT07298057?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 42 participants. The study started on 2026-02-06. Estimated completion is 2028-06.
What conditions does trial NCT07298057 study?
This clinical trial studies the following conditions: Periodontitis, Diabetes Mellitus Type 2.
What interventions are being tested in trial NCT07298057?
The interventions under investigation include: local antibiotic application of topical minocycline (DRUG), Scaling and Root Planing (PROCEDURE).
Who is sponsoring clinical trial NCT07298057?
This trial is sponsored by Case Western Reserve University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07298057 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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