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RECRUITING Phase 1

An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors

NCT07293754 · View on ClinicalTrials.gov ↗

Study Summary

This is an early phase trial designed to evaluate the safety, tolerability, and preliminary antitumor activity of RPTR-1-201 in adults with advanced solid tumors. The trial includes dose escalation and dose expansion parts and will evaluate RPTR-1-201 as monotherapy and in combination with an anti-PD-1 monoclonal antibody.

Interventions

  • DRUG RPTR-1-201
  • DRUG PD-1 / PD-L1 monoclonal antibody

Study Locations (1)

Michigan

  • START Midwest — Grand Rapids

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-12-12
Est. Completion 2029-04-15
Phase Phase 1

Sponsor

Repertoire Immune Medicines

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07293754

The ClinicalTrials.gov registry entry for NCT07293754 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Repertoire Immune Medicines, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Malignant Solid Tumor appearing as the primary indexed condition, and to 2 interventions — of which RPTR-1-201 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07293754 reports 1 study location spanning 1 distinct geographic area — top geographies include Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07293754 about?

NCT07293754 is a clinical study titled "An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors". This is an early phase trial designed to evaluate the safety, tolerability, and preliminary antitumor activity of RPTR-1-201 in adults with advanced solid tumors. The trial includes dose escalation and dose expansion parts and will evaluate RPTR-1-201 as monotherapy and in combination with an anti-P...

What is the current status of trial NCT07293754?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2025-12-12. Estimated completion is 2029-04-15.

What conditions does trial NCT07293754 study?

This clinical trial studies the following conditions: Advanced Malignant Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07293754?

The interventions under investigation include: RPTR-1-201 (DRUG), PD-1 / PD-L1 monoclonal antibody (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07293754?

This trial is sponsored by Repertoire Immune Medicines, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07293754 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial