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NCT07293754 · ClinicalTrials.gov registry record · Phase 1

An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors

A Phase 1 study of Advanced Malignant Solid Tumor, sponsored by Repertoire Immune Medicines.

Recruiting
Registry status
Phase 1
Development phase
150
Enrollment target
1
Study location

NCT07293754 is a Phase 1 study of Advanced Malignant Solid Tumor that is actively recruiting participants, run by Repertoire Immune Medicines. The registered enrollment target is 150 participants, above the 34-participant average among 3 other Advanced Malignant Solid Tumor trials with a reported enrollment target (341% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT07293754, a Phase 1 study of Advanced Malignant Solid Tumor, is actively recruiting participants, sponsored by Repertoire Immune Medicines.

RECRUITING
Registry status
Phase 1
Development phase
150 participants
Enrollment target
1
Study location

Study Summary

This is an early phase trial designed to evaluate the safety, tolerability, and preliminary antitumor activity of RPTR-1-201 in adults with advanced solid tumors. The trial includes dose escalation and dose expansion parts and will evaluate RPTR-1-201 as monotherapy and in combination with an anti-PD-1 monoclonal antibody.

Interventions

  • DRUG RPTR-1-201
  • DRUG PD-1 / PD-L1 monoclonal antibody

Study Locations (1)

Michigan

  • START Midwest - Grand Rapids

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-12-12
Est. Completion 2029-04-15
Phase Phase 1

Sponsor

Repertoire Immune Medicines

4 total trials

What the Registry Record Tells You About NCT07293754

The ClinicalTrials.gov registry entry for NCT07293754 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 34-participant average among 3 other Advanced Malignant Solid Tumor trials with a reported enrollment target (341% higher). The listed sponsor is Repertoire Immune Medicines, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Malignant Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which RPTR-1-201 is the first listed.

NCT07293754 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT07293754 about?

NCT07293754 is a clinical study titled "An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors". This is an early phase trial designed to evaluate the safety, tolerability, and preliminary antitumor activity of RPTR-1-201 in adults with advanced solid tumors. The trial includes dose escalation and dose expansion parts and will evaluate RPTR-1-201 as monotherapy and in combination with an anti-P...

What is the current status of trial NCT07293754?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 150 participants. The study started on 2025-12-12. Estimated completion is 2029-04-15.

What conditions does trial NCT07293754 study?

This clinical trial studies the following conditions: Advanced Malignant Solid Tumor.

What interventions are being tested in trial NCT07293754?

The interventions under investigation include: RPTR-1-201 (DRUG), PD-1 / PD-L1 monoclonal antibody (DRUG).

Who is sponsoring clinical trial NCT07293754?

This trial is sponsored by Repertoire Immune Medicines, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07293754 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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