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NCT07284082 · ClinicalTrials.gov registry record

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

A clinical trial, sponsored by University of California, San Francisco.

Recruiting
Registry status
90
Enrollment target

NCT07284082: Recruiting study, sponsored by University of California, San Francisco.

NCT07284082 is a clinical trial that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 90 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07284082 is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
90 participants
Enrollment target

Study Summary

Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.

Primary Outcome

sCD14 (monocyte activation), sCD163 (M2 macrophage activation), CRP (inflammation), IL-6 (inflammation), IP-10 (interferon-inducible protein), TNFα (inflammation), MCP-1 (inflammation), sTNFRI \& RII (inflammation). There are no units as they will be normalized based upon their interquartile range.

Interventions

  • DIAGNOSTIC_TEST Whole body MRI

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2026-04-17
Est. Completion 2030-03-01

What NCT07284082 shows while recruiting

NCT07284082 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Whole body MRI is the first listed.

NCT07284082 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07284082 about?

NCT07284082 is a clinical study titled "The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women". Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menop...

What is the current status of trial NCT07284082?

This trial is currently recruiting. The enrollment target is 90 participants. The study started on 2026-04-17. Estimated completion is 2030-03-01.

What interventions are being tested in trial NCT07284082?

The interventions under investigation include: Whole body MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT07284082?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT07284082, the US trial registry maintained by the National Library of Medicine. NCT07284082 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.