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NCT07283939 · ClinicalTrials.gov registry record · NA

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

A NA study, sponsored by Alliance for Clinical Trials in Oncology.

Recruiting
Registry status
NA
Development phase
420
Enrollment target

NCT07283939: Recruiting NA study, sponsored by Alliance for Clinical Trials in Oncology.

NCT07283939 is a NA study that is actively recruiting participants, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 420 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07283939, a NA study, is actively recruiting participants, sponsored by Alliance for Clinical Trials in Oncology.

RECRUITING
Registry status
NA
Development phase
420 participants
Enrollment target

Study Summary

This study seeks to learn whether using the PAGODA algorithm to guide chemotherapy dosing will lower the chance of unplanned delays during chemotherapy for cancer in the gastrointestinal system compared to usual care.

Primary Outcome

Will employ a generalized linear mixed effects model with logit link function, with a random patient effect to account for clustering of cycles within patients. Will test if additional random effects are needed (e.g., provider or clinic level). Statistical significance will be assessed at the 5% level. Delays will be assessed over cycles 2 through 7, and a delay will be defined as an interval of \> 18 days since day 1 of the previous cycle. An unplanned delay will be defined as any delay that wa

Interventions

  • DRUG Fluorouracil
  • DRUG Oxaliplatin
  • DRUG Folinic Acid
  • OTHER PAGODA algorithm

Trial Details

FieldValue
Enrollment Target 420 participants
Start Date 2026-02-13
Est. Completion 2030-05-02
Phase NA

What NCT07283939 shows while recruiting

NCT07283939 is an interventional study that assigns participants to a tested intervention. The registered 420 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 4 interventions - of which Fluorouracil is the first listed.

NCT07283939 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07283939 about?

NCT07283939 is a clinical study titled "Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays". This study seeks to learn whether using the PAGODA algorithm to guide chemotherapy dosing will lower the chance of unplanned delays during chemotherapy for cancer in the gastrointestinal system compared to usual care.

What is the current status of trial NCT07283939?

This trial is currently recruiting. It is a NA study. The enrollment target is 420 participants. The study started on 2026-02-13. Estimated completion is 2030-05-02.

What interventions are being tested in trial NCT07283939?

The interventions under investigation include: Fluorouracil (DRUG), Oxaliplatin (DRUG), Folinic Acid (DRUG), PAGODA algorithm (OTHER).

Who is sponsoring clinical trial NCT07283939?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07283939's enrollment target sits among peer trials

420 239th of 2000 higher than 1,761 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07283939, the US trial registry maintained by the National Library of Medicine. NCT07283939 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.