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NCT07250724 · ClinicalTrials.gov registry record

C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI.

A clinical trial of Clostridioides Difficile Infection Recurrence, sponsored by Bactolife A/S.

Recruiting
Registry status
60
Enrollment target
1
Study location

NCT07250724: Recruiting study of Clostridioides Difficile Infection Recurrence, sponsored by Bactolife A/S.

NCT07250724 is a study of Clostridioides Difficile Infection Recurrence that is actively recruiting participants, run by Bactolife A/S. The registered enrollment target is 60 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07250724, a study of Clostridioides Difficile Infection Recurrence, is actively recruiting participants, sponsored by Bactolife A/S.

RECRUITING
Registry status
60 participants
Enrollment target
1
Study location

Study Summary

Hospitals and clinics interested in participating in this multi-site study, please contact the people mentioned under "Contacts and Locations". The goal of this study is to map the risk of having a C. Difficile infection recurrence (rCDI) after being treated with standard-of-care antibiotics for a C. Difficile infection. The main questions it aims to answer are: * What is the recurrence rate of CDI in the 8 weeks following antibiotic treatment for a first recurrence of CDI? * Does toxin levels of Toxin A and/or B from C. Diff. at baseline predict CDI recurrence risk? Participants will: * Undergo standard of care Antibiotic treatment for first recurrence of CDI * Visit their clinic at 4 different visits over a time period of approximately 9 weeks. (Visits can also be performed remote/via phone call.)

Primary Outcome

CDI recurrence will be defined as the development of a new episode of diarrhoea (3 or more loose stools in 24 or fewer hours) associated with a positive stool test for toxigenic C. difficile following clinical cure of the initial CDI episode.

Interventions

  • OTHER Participants that are undergoing standard of care antibiotic treatment for their second C. Diff infection will be followed for 8 weeks after completing antibiotic treatment.

Study Locations (1)

Georgia

  • Emory University Hospital - Atlanta

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2026-02-01
Est. Completion 2026-10-15
Bactolife A/S

1 total trials

What NCT07250724 shows while recruiting

NCT07250724 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target.

The record links to 1 condition, with Clostridioides Difficile Infection Recurrence appearing as the primary indexed condition, and to 1 intervention - of which Participants that are undergoing standard of care antibiotic treatment for their second C. Diff infection will be followed for 8 weeks after completing antibiotic treatment. is the first listed.

NCT07250724 reports a single indexed study location in Georgia.

Frequently Asked Questions

What is clinical trial NCT07250724 about?

NCT07250724 is a clinical study titled "C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI.". Hospitals and clinics interested in participating in this multi-site study, please contact the people mentioned under "Contacts and Locations". The goal of this study is to map the risk of having a C. Difficile infection recurrence (rCDI) after being treated with standard-of-care antibiotics for a ...

What is the current status of trial NCT07250724?

This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2026-02-01. Estimated completion is 2026-10-15.

What conditions does trial NCT07250724 study?

This clinical trial studies the following conditions: Clostridioides Difficile Infection Recurrence.

What interventions are being tested in trial NCT07250724?

The interventions under investigation include: Participants that are undergoing standard of care antibiotic treatment for their second C. Diff infection will be followed for 8 weeks after completing antibiotic treatment. (OTHER).

Who is sponsoring clinical trial NCT07250724?

This trial is sponsored by Bactolife A/S, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07250724 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT07250724, the US trial registry maintained by the National Library of Medicine. NCT07250724 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.