Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
NCT07227116 · View on ClinicalTrials.gov ↗
Study Summary
This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis. Key Information: This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer. Participation remains completely voluntary, and your decision will not affect your current or future care. We deeply appreciate your support and commitment to advancing fertility research.
Conditions Studied
Study Locations (12)
Virginia
- Shady Grove Fertility — Fairfax
- Shady Grove Fertility — Norfolk
- Shady Grove Fertility — Richmond
Maryland
- Shady Grove Fertility — Rockville
- Shady Grove Fertility — Towson
North Carolina
- Shady Grove Fertility — Cary
- Shady Grove Fertility — Cary
Florida
- IVF Florida Reproductive Associates — Margate
Georgia
- Shady Grove Fertility — Atlanta
Illinois
- Fertility Center of Illinois — Highland Park
Pennsylvania
- Shady Grove Fertility — Chesterbrook
Santiago Metropolitan
- SGFertility Chile Medicina Reproductiva — Santiago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2025-11-01 |
| Est. Completion | 2026-06 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07227116
The ClinicalTrials.gov registry entry for NCT07227116 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 280 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shady Grove Fertility Reproductive Science Center, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Complex Aneuploidy appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07227116 reports 12 study locations spanning 8 distinct geographic areas — top geographies include Virginia, Maryland, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07227116 about?
NCT07227116 is a clinical study titled "Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos". This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whethe...
What is the current status of trial NCT07227116?
This trial is currently recruiting. The enrollment target is 280 participants. The study started on 2025-11-01. Estimated completion is 2026-06.
What conditions does trial NCT07227116 study?
This clinical trial studies the following conditions: Complex Aneuploidy, Chaotic Aneuploidy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT07227116?
This trial is sponsored by Shady Grove Fertility Reproductive Science Center, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07227116 being conducted?
This trial has 12 study locations across Florida, Georgia, Illinois, Maryland, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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