Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07227116 · ClinicalTrials.gov registry record
Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
A clinical trial of Complex Aneuploidy and Chaotic Aneuploidy, sponsored by Shady Grove Fertility Reproductive Science Center.
- Recruiting
- Registry status
- 280
- Enrollment target
- 12
- Study locations
NCT07227116: Recruiting study of Complex Aneuploidy and Chaotic Aneuploidy, sponsored by Shady Grove Fertility Reproductive Science Center.
NCT07227116 is a study of Complex Aneuploidy and Chaotic Aneuploidy that is actively recruiting participants, run by Shady Grove Fertility Reproductive Science Center. The registered enrollment target is 280 participants. The trial reports 12 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07227116, a study of Complex Aneuploidy and Chaotic Aneuploidy, is actively recruiting participants, sponsored by Shady Grove Fertility Reproductive Science Center.
- RECRUITING
- Registry status
- 280 participants
- Enrollment target
- 12
- Study locations
Study Summary
This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis. Key Information: This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer. Participation remains completely voluntary, and your decision will not affect your current or future care. We deeply appreciate your support and commitment to advancing fertility research.
Primary Outcome
To evaluate embryos with 3 or more chromosomes deemed aneuploid with NGS-based PGT-A by performing repeat biopsy and analyzing with NGS.
Conditions Studied
Study Locations (12)
Virginia
- Shady Grove Fertility - Fairfax
- Shady Grove Fertility - Norfolk
- Shady Grove Fertility - Richmond
Maryland
- Shady Grove Fertility - Rockville
- Shady Grove Fertility - Towson
North Carolina
- Shady Grove Fertility - Cary
- Shady Grove Fertility - Cary
Florida
- IVF Florida Reproductive Associates - Margate
Georgia
- Shady Grove Fertility - Atlanta
Illinois
- Fertility Center of Illinois - Highland Park
Pennsylvania
- Shady Grove Fertility - Chesterbrook
Santiago Metropolitan
- SGFertility Chile Medicina Reproductiva - Santiago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2025-11-01 |
| Est. Completion | 2026-06 |
What NCT07227116 shows while recruiting
NCT07227116 is an observational study that tracks outcomes without assigning an intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap.
The record links to 2 conditions, with Complex Aneuploidy appearing as the primary indexed condition, and to 0 interventions.
NCT07227116 lists 12 locations in 8 states (Virginia, Maryland, North Carolina).
Frequently Asked Questions
What is clinical trial NCT07227116 about?
NCT07227116 is a clinical study titled "Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos". This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whethe...
What is the current status of trial NCT07227116?
This trial is currently recruiting. The enrollment target is 280 participants. The study started on 2025-11-01. Estimated completion is 2026-06.
What conditions does trial NCT07227116 study?
This clinical trial studies the following conditions: Complex Aneuploidy, Chaotic Aneuploidy.
Who is sponsoring clinical trial NCT07227116?
This trial is sponsored by Shady Grove Fertility Reproductive Science Center, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07227116 being conducted?
This trial has 12 study locations across Florida, Georgia, Illinois, Maryland, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04084730 · 280 participants · Phase 2
Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
- NCT04518657 · 280 participants · NA
Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
- NCT04634916 · 280 participants · NA
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
- NCT04829617 · 280 participants · NA
Promoting Well-being and Health in Heart Failure
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI