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NCT07226245 · ClinicalTrials.gov registry record · Phase 4

Methadone Pharmacokinetics in Cardiac Surgery

A Phase 4 study, sponsored by Wake Forest University Health Sciences.

Not yet
Registry status
Phase 4
Development phase
69
Enrollment target

NCT07226245 is a Phase 4 study that has not yet begun recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 69 participants.

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The verdict

NCT07226245, a Phase 4 study, has not yet begun recruiting, sponsored by Wake Forest University Health Sciences.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
69 participants
Enrollment target

Study Summary

Cardiac surgery frequently leads to significant postoperative pain, with multiple different drug regimens being utilized (both opioid and non-opioid) in an attempt to alleviate this surgical pain. Methadone is currently one of the drugs that is being utilized to help control the pain. It can be given during and/or after surgery. This study hopes to identify the optimal dose of methadone to use to treat this surgical pain.

Interventions

  • DRUG Single dose of methadone
  • DRUG Split dose of methadone
  • DRUG Balanced split dose of methadone

Trial Details

FieldValue
Enrollment Target 69 participants
Start Date 2026-09
Est. Completion 2026-12-30
Phase Phase 4

Sponsor

Wake Forest University Health Sciences

1,140 total trials

What the Registry Record Tells You About NCT07226245

The ClinicalTrials.gov registry entry for NCT07226245 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 69 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Single dose of methadone is the first listed.

NCT07226245 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07226245 about?

NCT07226245 is a clinical study titled "Methadone Pharmacokinetics in Cardiac Surgery". Cardiac surgery frequently leads to significant postoperative pain, with multiple different drug regimens being utilized (both opioid and non-opioid) in an attempt to alleviate this surgical pain. Methadone is currently one of the drugs that is being utilized to help control the pain. It can be give...

What is the current status of trial NCT07226245?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 69 participants. The study started on 2026-09. Estimated completion is 2026-12-30.

What interventions are being tested in trial NCT07226245?

The interventions under investigation include: Single dose of methadone (DRUG), Split dose of methadone (DRUG), Balanced split dose of methadone (DRUG).

Who is sponsoring clinical trial NCT07226245?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.