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NCT07225400 · ClinicalTrials.gov registry record · NA
Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment
A NA study, sponsored by Albert Einstein College of Medicine.
- Not yet
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT07225400: Clinical Trial NA study, sponsored by Albert Einstein College of Medicine.
NCT07225400 is a NA study that has not yet begun recruiting, run by Albert Einstein College of Medicine. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07225400, a NA study, has not yet begun recruiting, sponsored by Albert Einstein College of Medicine.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
The goal of this one-arm clinical trial is to determine whether participants with mild cognitive impairment (MCI) can successfully navigate a virtual reality (VR) maze. The VR maze is designed as a training tool aimed at improving participants' spatial navigation abilities. Main Aims: 1. To determine whether at least 70% of older adults enrolled in the study can complete twenty-four 50-minute training sessions over a 4-month period. 2. To assess whether combining virtual reality with EEG recordings can be used to measure brain activation and changes in brain activation associated with spatial navigation learning. Participants will: 1. Walk in an open, unobstructed space while wearing VR goggles. 2. Explore up to fifty different virtual mazes in sequence and attempt to find their way through each one.
Primary Outcome
Change in immediate maze time will be assessed as a Behavioral marker of change and determined using the floor maze test (FMT), which combines navigation with walking. Participants will be positioned at the entry point of the FMT and instructed to find their way to the exit point of the FMT. A fixed 15-second planning period will be given to plan the route. The time elapsed from the end of the planning period to successful exit (i.e., IMT), in seconds, will be recorded. Paired t-tests will be us
Interventions
- BEHAVIORAL Spatial Navigation training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2026-08-01 |
| Est. Completion | 2027-12-23 |
| Phase | NA |
What is known before NCT07225400 opens enrollment
NCT07225400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Spatial Navigation training is the first listed.
NCT07225400 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07225400 about?
NCT07225400 is a clinical study titled "Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment". The goal of this one-arm clinical trial is to determine whether participants with mild cognitive impairment (MCI) can successfully navigate a virtual reality (VR) maze. The VR maze is designed as a training tool aimed at improving participants' spatial navigation abilities. Main Aims: 1. To determ...
What is the current status of trial NCT07225400?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2026-08-01. Estimated completion is 2027-12-23.
What interventions are being tested in trial NCT07225400?
The interventions under investigation include: Spatial Navigation training (BEHAVIORAL).
Who is sponsoring clinical trial NCT07225400?
This trial is sponsored by Albert Einstein College of Medicine, which has 175 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07225400's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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