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NCT07225049 · ClinicalTrials.gov registry record · NA
Integrated PTSD and Chronic Pain Treatment
A NA study of Chronic Pain and PTSD, sponsored by Weill Medical College of Cornell University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07225049: Recruiting NA study of Chronic Pain and PTSD, sponsored by Weill Medical College of Cornell University.
NCT07225049 is a NA study of Chronic Pain and PTSD that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 20 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07225049, a NA study of Chronic Pain and PTSD, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Posttraumatic stress disorder (PTSD) occurs in approximately 7% of adults in the general population. PTSD greatly impacts quality of life and often co-occurs with other conditions such as chronic pain. Individuals with co-morbid PTSD and chronic pain demonstrate higher PTSD symptoms and pain (as well as greater anxiety, depression, disability, and opioid use) compared to those with only one of those conditions. Gold standard treatments exist for both PTSD (e.g., Prolonged Exposure; PE) and chronic pain (e.g., Cognitive Behavioral Therapy for Chronic Pain; CBT-CP) and are generally offered sequentially (i.e., one at a time for the condition that is most prominent). Treating these conditions separately may overlook their interconnected nature, which may reduce efficacy and increase dropout. Thus, there is a need for an intervention to target both simultaneously, which may be more effective and efficient than treating conditions sequentially. This is a single-arm pilot study to assess the feasibility and acceptability of an integrated treatment for adults with comorbid PTSD and chronic pain. The intervention consists of 12 90-minute virtual psychotherapy sessions scheduled twice per week. The treatment draws from modules in PE and CBT-CP including psychoeducation, exposure to feared/avoided situations and activities, processing of exposures, behavioral activation, breathing and relaxation techniques, sleep hygiene, symptom monitoring, and structured homework assignments. Baseline and post-treatment assessments will be conducted.
Primary Outcome
Feasibility assessment will include number of participants screened defined as number of individuals who complete our initial eligibility screener.
Conditions Studied
Interventions
- BEHAVIORAL Integrated Treatment for PTSD and Chronic Pain
Study Locations (1)
New York
- Weill Cornell Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-12-08 |
| Est. Completion | 2027-08 |
| Phase | NA |
What NCT07225049 shows while recruiting
NCT07225049 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 1 intervention - of which Integrated Treatment for PTSD and Chronic Pain is the first listed.
NCT07225049 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT07225049 about?
NCT07225049 is a clinical study titled "Integrated PTSD and Chronic Pain Treatment". Posttraumatic stress disorder (PTSD) occurs in approximately 7% of adults in the general population. PTSD greatly impacts quality of life and often co-occurs with other conditions such as chronic pain. Individuals with co-morbid PTSD and chronic pain demonstrate higher PTSD symptoms and pain (as wel...
What is the current status of trial NCT07225049?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-12-08. Estimated completion is 2027-08.
What conditions does trial NCT07225049 study?
This clinical trial studies the following conditions: Chronic Pain, PTSD.
What interventions are being tested in trial NCT07225049?
The interventions under investigation include: Integrated Treatment for PTSD and Chronic Pain (BEHAVIORAL).
Who is sponsoring clinical trial NCT07225049?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07225049 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07225049's enrollment target sits among peer trials
20 271st of 301 higher than 28 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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