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NCT07224282 · ClinicalTrials.gov registry record · Early Phase 1
The Effects of Ketone Supplements With Carbohydrates on Cycling Performance Above Lactate Threshold
A Early Phase 1 study, sponsored by University of Oklahoma.
- Not yet
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
NCT07224282: Clinical Trial Early Phase 1 study, sponsored by University of Oklahoma.
NCT07224282 is a Early Phase 1 study that has not yet begun recruiting, run by University of Oklahoma. The registered enrollment target is 15 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07224282, a Early Phase 1 study, has not yet begun recruiting, sponsored by University of Oklahoma.
- NOT YET RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to determine whether a ketone supplement with carbohydrates extends time to fatigue during cycling compared with a carbohydrate-only supplement in healthy, trained cyclists aged 18-55. The main questions it aims to answer are: Is the time to fatigue increased with ketone supplementation and carbohydrates compared to carbohydrates alone? Will ketone supplementation with carbohydrates produce lower blood lactate concentrations compared to carbohydrates alone? Participants will: * Perform a staged maximal cycling exercise test on a stationary bicycle. * Finger prick to obtain a drop of blood for lactate measurements. * Wear a mask connected to a metabolic cart to measure breath contents. * Perform a cycling exercise test to fatigue for at least one hour. * Consume either a ketone supplement with carbohydrates or a carbohydrate supplement during the exercise at least 4 times. * Finger prick to obtain a drop of blood to measure blood lactate, ketones, and glucose.
Interventions
- DIETARY_SUPPLEMENT Carbohydrate
- DIETARY_SUPPLEMENT Ketone supplementation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2025-11-17 |
| Est. Completion | 2026-05-03 |
| Phase | Early Phase 1 |
What is known before NCT07224282 opens enrollment
NCT07224282 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Carbohydrate is the first listed.
NCT07224282 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07224282 about?
NCT07224282 is a clinical study titled "The Effects of Ketone Supplements With Carbohydrates on Cycling Performance Above Lactate Threshold". The goal of this clinical trial is to determine whether a ketone supplement with carbohydrates extends time to fatigue during cycling compared with a carbohydrate-only supplement in healthy, trained cyclists aged 18-55. The main questions it aims to answer are: Is the time to fatigue increased with...
What is the current status of trial NCT07224282?
This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2025-11-17. Estimated completion is 2026-05-03.
What interventions are being tested in trial NCT07224282?
The interventions under investigation include: Carbohydrate (DIETARY_SUPPLEMENT), Ketone supplementation (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07224282?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07224282's enrollment target sits among peer trials
15 1403rd of 2000 higher than 527 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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