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NCT07223710 · ClinicalTrials.gov registry record · Phase 1
Improving Walking After Spinal Cord Injury
A Phase 1 study, sponsored by Shirley Ryan AbilityLab.
- Not yet
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT07223710 is a Phase 1 study that has not yet begun recruiting, run by Shirley Ryan AbilityLab. The registered enrollment target is 20 participants.
The verdict
NCT07223710, a Phase 1 study, has not yet begun recruiting, sponsored by Shirley Ryan AbilityLab.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
Locomotor recovery is one of the most important goals of individuals with spinal cord injury (SCI). Ambulatory deficits severely impact daily functions resulting in lower quality of life for people living with paralysis due to SCI. Although studies have shown that locomotor training improves locomotor function in people with chronic SCI, the benefits remain limited. Our overall hypothesis is that we can engage additional descending motor pathways, such as the reticulospinal tract (RST), to improve locomotor function in humans with chronic incomplete SCI. In this study we propose to test the effects of a novel intervention that uses repeated paired loud auditory and electrical stimulation of muscle afferents combined with locomotor training on walking speed and voluntary muscle strength.
Interventions
- DEVICE Sham stimulation
- BEHAVIORAL Locomotor Training
- DEVICE Paired Associative Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-11-15 |
| Est. Completion | 2026-07-30 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07223710
The ClinicalTrials.gov registry entry for NCT07223710 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shirley Ryan AbilityLab, which has 138 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Sham stimulation is the first listed.
NCT07223710 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07223710 about?
NCT07223710 is a clinical study titled "Improving Walking After Spinal Cord Injury". Locomotor recovery is one of the most important goals of individuals with spinal cord injury (SCI). Ambulatory deficits severely impact daily functions resulting in lower quality of life for people living with paralysis due to SCI. Although studies have shown that locomotor training improves locomot...
What is the current status of trial NCT07223710?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2025-11-15. Estimated completion is 2026-07-30.
What interventions are being tested in trial NCT07223710?
The interventions under investigation include: Sham stimulation (DEVICE), Locomotor Training (BEHAVIORAL), Paired Associative Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07223710?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
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