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NCT07223437 · ClinicalTrials.gov registry record · NA

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

A NA study, sponsored by University of Tennessee Graduate School of Medicine.

Recruiting
Registry status
NA
Development phase
81
Enrollment target

NCT07223437 is a NA study that is actively recruiting participants, run by University of Tennessee Graduate School of Medicine. The registered enrollment target is 81 participants.

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The verdict

NCT07223437, a NA study, is actively recruiting participants, sponsored by University of Tennessee Graduate School of Medicine.

RECRUITING
Registry status
NA
Development phase
81 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the effects of Blood Flow Restriction (BFR) training on walking function, health-related quality of life, and safety among adults with Peripheral Arterial Disease (PAD). The main aims of the study are: 1. Evaluate change in walking function among patients with PAD undergoing BFR training. The investigators will assess change in Six-Minute Walk Test (6MWT) distance from baseline to post-intervention and 3-month follow-up to compare functional improvements between the BFR group and the two control groups 2. Assess changes in health-related quality of life among patients with PAD undergoing BFR training. The investigators will use the EuroQol 5-Dimension 5-Level (EQ-5D-5L) scale to evaluate quality-of-life changes from baseline to post-intervention and 3-month follow-up across all study arms 3. Evaluate the safety and feasibility of a supervised BFR training program for patients with PAD. The investigators will compare adverse event (AE) and serious adverse event (SAE) rates across study arms, while also monitoring sessional ratings of perceived exertion (RPE), dyspnea, and claudication pain as indicators of symptom response and exercise tolerance. Feasibility will be assessed through enrollment success, intervention adherence, and retention rates across groups

Interventions

  • BEHAVIORAL Blood Flow Restriction Cuff System
  • BEHAVIORAL Low-load Resistance Training
  • BEHAVIORAL High-load Resistance Training

Trial Details

FieldValue
Enrollment Target 81 participants
Start Date 2026-04-27
Est. Completion 2027-04-27
Phase NA

What the Registry Record Tells You About NCT07223437

The ClinicalTrials.gov registry entry for NCT07223437 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 81 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Tennessee Graduate School of Medicine, which has 20 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Blood Flow Restriction Cuff System is the first listed.

NCT07223437 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07223437 about?

NCT07223437 is a clinical study titled "REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center". The purpose of this study is to evaluate the effects of Blood Flow Restriction (BFR) training on walking function, health-related quality of life, and safety among adults with Peripheral Arterial Disease (PAD). The main aims of the study are: 1. Evaluate change in walking function among patients w...

What is the current status of trial NCT07223437?

This trial is currently recruiting. It is a NA study. The enrollment target is 81 participants. The study started on 2026-04-27. Estimated completion is 2027-04-27.

What interventions are being tested in trial NCT07223437?

The interventions under investigation include: Blood Flow Restriction Cuff System (BEHAVIORAL), Low-load Resistance Training (BEHAVIORAL), High-load Resistance Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT07223437?

This trial is sponsored by University of Tennessee Graduate School of Medicine, which has 20 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.