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NCT07222111 · ClinicalTrials.gov registry record · NA
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
A NA study of T Cell Response to Dried Plum and Vitamin D Influence on Immune Response, sponsored by Indiana University.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07222111: Recruiting NA study of T Cell Response to Dried Plum and Vitamin D Influence on Immune Response, sponsored by Indiana University.
NCT07222111 is a NA study of T Cell Response to Dried Plum and Vitamin D Influence on Immune Response that is actively recruiting participants, run by Indiana University. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07222111, a NA study of T Cell Response to Dried Plum and Vitamin D Influence on Immune Response, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women. The purpose of this clinical trial is to understand how dried plums mediate their effects on bone. The main questions the study will answer are: 1. Does adding dried plums to the diet alter immune cell function? 2. Does dried plum alter gut microbes? 3. Does a person's vitamin D status influence this response? Researcher will compare the response following consumption of the normal diet to supplementing the diet with dried plums. Participant will: 1. Consume their normal diet or supplement their normal diet dried plums for four week periods over the course of 3-4 months. 2. Complete 5 study visits scheduled. 3. Perform some physical function tests and have a bone density scan at the beginning of the study. 4. Complete questionnaires, a 3-day food record, and provide stool and blood samples at 4 different timepoints during the study. 5. Record information about their bowel habits
Primary Outcome
Change in the relative abundance of circulating Th17 cells in response to dried plum supplementation compared to control arm of the study will be reported.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Dried plums
Study Locations (1)
Indiana
- IU Health University Hospital Clinical Research Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-09-02 |
| Est. Completion | 2028-08-30 |
| Phase | NA |
What NCT07222111 shows while recruiting
NCT07222111 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with T Cell Response to Dried Plum appearing as the primary indexed condition, and to 1 intervention - of which Dried plums is the first listed.
NCT07222111 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07222111 about?
NCT07222111 is a clinical study titled "Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women". Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women. The purpose of this clinical trial is to understand how dried plums mediate their effects on bone. The main questions the study will answer are: 1. Does adding dr...
What is the current status of trial NCT07222111?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-09-02. Estimated completion is 2028-08-30.
What conditions does trial NCT07222111 study?
This clinical trial studies the following conditions: T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function.
What interventions are being tested in trial NCT07222111?
The interventions under investigation include: Dried plums (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07222111?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222111 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07222111's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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