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NCT07221994 · ClinicalTrials.gov registry record · NA
Blood Flow Restriction and Exercise in Parkinson's Disease
A NA study of Parkinson Disease, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 4
- Enrollment target
- 1
- Study location
NCT07221994 is a NA study of Parkinson Disease that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 4 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07221994, a NA study of Parkinson Disease, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn whether training with blood flow restriction (BFR), combined with aerobic exercise (performing stepping on a Nu-Step exercise machine), can help improve mobility and other outcomes in people with progressed Parkinson's disease. The investigators hypothesize that training with BFR and aerobic exercise will produce enhanced outcomes related to mobility and quality of life. BFR uses inflatable cuffs placed on participants' upper legs to gently reduce blood flow to the legs while exercising. This has been shown in studies in older adults and Parkinson's disease to improve strength while training with lighter loads, which may be helpful for people with Parkinson's. Participants will be asked to complete 2 weekly training sessions (approximately 30 minutes each) for 8 weeks consisting of supervised aerobic stepping exercise on a Nu-step machine with BFR application during timed intervals. In addition to the training sessions, participants will be asked to periodically perform confidential surveys and tests related to function and disease symptoms, and wear a provided smartwatch (which can be kept upon successful completion of the study). All sessions involve individual monitoring and medical supervision by licensed physical therapists as well as access to all necessary equipment.
Conditions Studied
Interventions
- DEVICE Blood flow restriction (BFR) and aerobic exercise via recumbent stepping (Nu-Step)
Study Locations (1)
California
- UCSF Health & Wellness Center (UCSF Mission Bay) - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2025-11-21 |
| Est. Completion | 2026-03 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07221994
The ClinicalTrials.gov registry entry for NCT07221994 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Blood flow restriction (BFR) and aerobic exercise via recumbent stepping (Nu-Step) is the first listed.
NCT07221994 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT07221994 about?
NCT07221994 is a clinical study titled "Blood Flow Restriction and Exercise in Parkinson's Disease". The goal of this clinical trial is to learn whether training with blood flow restriction (BFR), combined with aerobic exercise (performing stepping on a Nu-Step exercise machine), can help improve mobility and other outcomes in people with progressed Parkinson's disease. The investigators hypothesiz...
What is the current status of trial NCT07221994?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 4 participants. The study started on 2025-11-21. Estimated completion is 2026-03.
What conditions does trial NCT07221994 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT07221994?
The interventions under investigation include: Blood flow restriction (BFR) and aerobic exercise via recumbent stepping (Nu-Step) (DEVICE).
Who is sponsoring clinical trial NCT07221994?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07221994 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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