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NCT07221266 · ClinicalTrials.gov registry record · NA

Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs

A NA study, sponsored by University of Texas, El Paso.

Recruiting
Registry status
NA
Development phase
45
Enrollment target

NCT07221266: Recruiting NA study, sponsored by University of Texas, El Paso.

NCT07221266 is a NA study that is actively recruiting participants, run by University of Texas, El Paso. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07221266, a NA study, is actively recruiting participants, sponsored by University of Texas, El Paso.

RECRUITING
Registry status
NA
Development phase
45 participants
Enrollment target

Study Summary

Parkinson's disease (PD) is a progressive neurological condition that can affect movement, balance, endurance, and overall quality of life. Exercise is widely recognized as one of the most effective non-pharmacological treatments to help people with PD maintain function and independence. However, not all exercise programs produce the same results, and more research is needed to understand which types of exercise offer the greatest physical and physiological benefits. This study is designed to examine how different types of structured exercise programs influence motor function, cardiorespiratory fitness, and markers of overall health in individuals with Parkinson's disease. The goal is to better understand how exercise can be used to improve movement, daily activities, and general well-being, as well as how it affects the body at a physiological level. Participants will be adults diagnosed with idiopathic Parkinson's disease who are medically stable and able to safely participate in exercise. Before beginning the study, participants will complete screening procedures to ensure safety and eligibility. Eligible participants will then be assigned to one of several supervised exercise interventions conducted over a defined period. Each exercise program is designed to improve movement and function but differs in structure or training emphasis (for example, aerobic, functional, or task-specific activity). Exercise sessions will take place under the supervision of licensed physical therapist. Each session will include warm-up, exercise, and cool-down components. Intensity will be monitored using heart rate and perceived exertion to ensure safety and appropriate challenge. Participants will attend sessions multiple times per week for 8 weeks. Researchers will collect information about movement abilities, balance, walking, endurance, and daily function using standardized physical therapy assessments such as gait tests, balance measures, and questionnaires related to quali

Primary Outcome

The Mini-Balance Evaluation Systems Test (Mini-BESTest) assesses anticipatory control, reactive postural control, sensory orientation, and dynamic gait. Total score range 0-28; higher scores indicate better balance.

Interventions

  • BEHAVIORAL Guided Cycling
  • BEHAVIORAL Non-Contact Boxing
  • BEHAVIORAL Traditional Physical Therapy Program (Standard of Care)

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2026-04-21
Est. Completion 2027-06-30
Phase NA
University of Texas, El Paso

17 total trials

What NCT07221266 shows while recruiting

NCT07221266 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 3 interventions - of which Guided Cycling is the first listed.

NCT07221266 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07221266 about?

NCT07221266 is a clinical study titled "Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs". Parkinson's disease (PD) is a progressive neurological condition that can affect movement, balance, endurance, and overall quality of life. Exercise is widely recognized as one of the most effective non-pharmacological treatments to help people with PD maintain function and independence. However, no...

What is the current status of trial NCT07221266?

This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2026-04-21. Estimated completion is 2027-06-30.

What interventions are being tested in trial NCT07221266?

The interventions under investigation include: Guided Cycling (BEHAVIORAL), Non-Contact Boxing (BEHAVIORAL), Traditional Physical Therapy Program (Standard of Care) (BEHAVIORAL).

Who is sponsoring clinical trial NCT07221266?

This trial is sponsored by University of Texas, El Paso, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07221266's enrollment target sits among peer trials

45 1411th of 2000 higher than 578 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07221266, the US trial registry maintained by the National Library of Medicine. NCT07221266 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.