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NCT07216209 · ClinicalTrials.gov registry record · NA

The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer

A NA study, sponsored by University of Arizona.

Recruiting
Registry status
NA
Development phase
48
Enrollment target

NCT07216209 is a NA study that is actively recruiting participants, run by University of Arizona. The registered enrollment target is 48 participants.

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The verdict

NCT07216209, a NA study, is actively recruiting participants, sponsored by University of Arizona.

RECRUITING
Registry status
NA
Development phase
48 participants
Enrollment target

Study Summary

There is increased interest and knowledge about the lung cancer tumor microenvironment (TME). Investigators hypothesize that patients with better baseline physiologic health will have better post-operative outcomes and that strenuous exercise will alter the TME and genetic make-up of the tumor, improving the tumor immune response. Investigators aim to identify the peri-operative and clinical outcomes that differ based on pre-operative VO2max, HRV and resting heart rate following resection of early-stage lung cancer. The physiologic states that are individual and measurable with wearable devices include but are not limited to VO2max, heart rate variability (HRV), and average resting heart rate. Investgators hypothesize that a patient's pre-operative physiologic function with higher VO2max, HRV and lower resting heart rate will be associated with improved peri-operative and post-operative outcomes. Second, investigators will compare alterations in TME based on targeted pre-operative exercise (60-80% of their VO2 max for 75min/week x2 weeks) compared to normal activity adults following resection of early-stage lung cancer. Investigators hypothesize that strenuous exercise in the pre-operative period will impact the TME by increasing levels of cytokines.

Interventions

  • BEHAVIORAL EXERCISE TRAINING WITH OR WITHOUT MEDICATION

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2026-01-13
Est. Completion 2030-01-15
Phase NA

Sponsor

University of Arizona

349 total trials

What the Registry Record Tells You About NCT07216209

The ClinicalTrials.gov registry entry for NCT07216209 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arizona, which has 349 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which EXERCISE TRAINING WITH OR WITHOUT MEDICATION is the first listed.

NCT07216209 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07216209 about?

NCT07216209 is a clinical study titled "The Impact of Exercise on the Tumor Microenvironment in Patients With Lung Cancer". There is increased interest and knowledge about the lung cancer tumor microenvironment (TME). Investigators hypothesize that patients with better baseline physiologic health will have better post-operative outcomes and that strenuous exercise will alter the TME and genetic make-up of the tumor, impr...

What is the current status of trial NCT07216209?

This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2026-01-13. Estimated completion is 2030-01-15.

What interventions are being tested in trial NCT07216209?

The interventions under investigation include: EXERCISE TRAINING WITH OR WITHOUT MEDICATION (BEHAVIORAL).

Who is sponsoring clinical trial NCT07216209?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.