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NCT07214389 · ClinicalTrials.gov registry record · NA

PRoducing Outcome Measures for OTP Quality Improvement

A NA study, sponsored by RTI International.

Recruiting
Registry status
NA
Development phase
4,500
Enrollment target

NCT07214389: Recruiting NA study, sponsored by RTI International.

NCT07214389 is a NA study that is actively recruiting participants, run by RTI International. The registered enrollment target is 4,500 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (221% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07214389, a NA study, is actively recruiting participants, sponsored by RTI International.

RECRUITING
Registry status
NA
Development phase
4,500 participants
Enrollment target

Study Summary

This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet many people leave treatment early. The project will compare two approaches that provide clinics with retention/outcome quality measures and a quality-improvement (QI) toolkit-either alone or with added facilitation-against usual care. Forty-five BayMark OTPs in multiple states will be randomly assigned to one of three groups: (1) quality measures + QI toolkit; (2) quality measures + QI toolkit + external QI facilitation; or (3) usual care. The primary outcome is 90-day retention in treatment, measured from OTP electronic health records and Medicaid claims. Secondary outcomes include emergency department visits, hospitalizations, overdoses, and mortality. Findings will identify practical, scalable strategies to improve patient retention in OTPs.

Primary Outcome

The primary endpoint in the quantitative analyses will be the OTP's 90-day treatment retention rate.

Interventions

  • BEHAVIORAL Quality Measures (Audit and Feedback)
  • BEHAVIORAL Quality Improvement (QI) Toolkit
  • BEHAVIORAL External QI Facilitation

Trial Details

FieldValue
Enrollment Target 4,500 participants
Start Date 2025-10-03
Est. Completion 2027-12
Phase NA
RTI International

45 total trials

What NCT07214389 shows while recruiting

NCT07214389 is an interventional study that assigns participants to a tested intervention. Its 4,500 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (221% higher).

The record links to 0 conditions, and to 3 interventions - of which Quality Measures (Audit and Feedback) is the first listed.

NCT07214389 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07214389 about?

NCT07214389 is a clinical study titled "PRoducing Outcome Measures for OTP Quality Improvement". This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet many people leave treatment early. The project will compare two approaches that provide clinics with retention/outcome quality measures and a ...

What is the current status of trial NCT07214389?

This trial is currently recruiting. It is a NA study. The enrollment target is 4,500 participants. The study started on 2025-10-03. Estimated completion is 2027-12.

What interventions are being tested in trial NCT07214389?

The interventions under investigation include: Quality Measures (Audit and Feedback) (BEHAVIORAL), Quality Improvement (QI) Toolkit (BEHAVIORAL), External QI Facilitation (BEHAVIORAL).

Who is sponsoring clinical trial NCT07214389?

This trial is sponsored by RTI International, which has 45 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07214389's enrollment target sits among peer trials

4,500 29th of 2000 higher than 1,971 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07214389, the US trial registry maintained by the National Library of Medicine. NCT07214389 (large enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.