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NCT07210775 · ClinicalTrials.gov registry record · Phase 1
Topical Imiquimod Treatment of Oral Dysplasia
A Phase 1 study of Oral Dysplasia and Leukoplakia, sponsored by University of Southern California.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07210775: Recruiting Phase 1 study of Oral Dysplasia and Leukoplakia, sponsored by University of Southern California.
NCT07210775 is a Phase 1 study of Oral Dysplasia and Leukoplakia that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07210775, a Phase 1 study of Oral Dysplasia and Leukoplakia, is actively recruiting participants, sponsored by University of Southern California.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine the effectiveness of imiquimod in treating oral dysplasia in adult patients. Imiquimod 5% cream could be a safe and practical treatment for oral epithelial dysplasia (a precancerous change in the mouth). The main questions it aims to answer are: 1. Does imiquimod help to make the lesions smaller and make the abnormal cell changes less severe? 2. How can we make this treatment safer and more feasible? Participants will apply topical imiquimod cream to treat the oral dysplasia and receive two follow-up biopsies after the treatment.
Primary Outcome
Clinical response: Change in the size of the lesion. Measurement of the lesion and scored according to RECIST criteria
Conditions Studied
Interventions
- DRUG Imiquimod (topical use)
Study Locations (1)
California
- OralCare PreCancer and Pain Clinic - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2027-10-01 |
| Phase | Phase 1 |
What NCT07210775 shows while recruiting
NCT07210775 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 3 conditions, with Oral Dysplasia appearing as the primary indexed condition, and to 1 intervention - of which Imiquimod (topical use) is the first listed.
NCT07210775 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07210775 about?
NCT07210775 is a clinical study titled "Topical Imiquimod Treatment of Oral Dysplasia". The goal of this clinical trial is to determine the effectiveness of imiquimod in treating oral dysplasia in adult patients. Imiquimod 5% cream could be a safe and practical treatment for oral epithelial dysplasia (a precancerous change in the mouth). The main questions it aims to answer are: 1. Do...
What is the current status of trial NCT07210775?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2025-10-01. Estimated completion is 2027-10-01.
What conditions does trial NCT07210775 study?
This clinical trial studies the following conditions: Oral Dysplasia, Leukoplakia, Leukoplakia Oral.
What interventions are being tested in trial NCT07210775?
The interventions under investigation include: Imiquimod (topical use) (DRUG).
Who is sponsoring clinical trial NCT07210775?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07210775 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Oral Dysplasia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07210775's enrollment target sits among peer trials
20 1630th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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