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NCT07207122 · ClinicalTrials.gov registry record · NA
Effects of Transcranial Ultrasound Stimulation (TUS) on Neurological and Cognitive Outcomes in Neurodegenerative Diseases
A NA study of Parkinson Disease and Mild Cognitive Impairment, sponsored by Sanmai Technologies PBC dba Sanmai.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07207122: Recruiting NA study of Parkinson Disease and Mild Cognitive Impairment, sponsored by Sanmai Technologies PBC dba Sanmai.
NCT07207122 is a NA study of Parkinson Disease and Mild Cognitive Impairment that is actively recruiting participants, run by Sanmai Technologies PBC dba Sanmai. The registered enrollment target is 20 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07207122, a NA study of Parkinson Disease and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Sanmai Technologies PBC dba Sanmai.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the safety and efficacy of transcranial focused ultrasound neuromodulation in improving neural function, cognitive and behavioral performance, and quality of life for patients with neurodegenerative diseases.
Primary Outcome
The MDS-UPDRS Part III is a clinician-administered assessment of motor function in Parkinson's disease. It includes 18 items with 33 individual ratings, each scored from 0 (normal) to 4 (severe), with a total score range of 0 to 132. Higher scores indicate worse motor impairment. Assessments will be conducted in the OFF-medication state by trained, blinded raters using standardized procedures. The outcome measure is defined as the change from baseline in total score at post-treatment milestones
Conditions Studied
Interventions
- DEVICE Transcranial focused ultrasound modulation administered to a region involved in disease pathology.
Study Locations (1)
California
- The Regenesis Project - Santa Monica
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-10-08 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT07207122 shows while recruiting
NCT07207122 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower).
The record links to 7 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Transcranial focused ultrasound modulation administered to a region involved in disease pathology. is the first listed.
NCT07207122 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07207122 about?
NCT07207122 is a clinical study titled "Effects of Transcranial Ultrasound Stimulation (TUS) on Neurological and Cognitive Outcomes in Neurodegenerative Diseases". The purpose of this study is to evaluate the safety and efficacy of transcranial focused ultrasound neuromodulation in improving neural function, cognitive and behavioral performance, and quality of life for patients with neurodegenerative diseases.
What is the current status of trial NCT07207122?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-10-08. Estimated completion is 2026-08.
What conditions does trial NCT07207122 study?
This clinical trial studies the following conditions: Parkinson Disease, Mild Cognitive Impairment, Parkinson's Disease (PD), Alzheimer's Disease (AD), Parkinson's Disease Dementia (PDD).
What interventions are being tested in trial NCT07207122?
The interventions under investigation include: Transcranial focused ultrasound modulation administered to a region involved in disease pathology. (DEVICE).
Who is sponsoring clinical trial NCT07207122?
This trial is sponsored by Sanmai Technologies PBC dba Sanmai, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07207122 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07207122's enrollment target sits among peer trials
20 241st of 297 higher than 46 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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