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NCT07204990 · ClinicalTrials.gov registry record · NA
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
A NA study, sponsored by Telethon Kids Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 1,400
- Enrollment target
NCT07204990: Recruiting NA study, sponsored by Telethon Kids Institute.
NCT07204990 is a NA study that is actively recruiting participants, run by Telethon Kids Institute. The registered enrollment target is 1,400 participants, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07204990, a NA study, is actively recruiting participants, sponsored by Telethon Kids Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,400 participants
- Enrollment target
Study Summary
During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking up in (awake removal); or (2) the ETT is removed while still under anaesthesia(deep removal). Currently there is no evidence to suggest either technique is safer - deep removal of the ETT may decrease the risk of overall airway complications, including cough and desaturations. However, it may be associated with increased airway obstruction compared with awake extubation in paediatric patients. In our institution, a further technique has become increasingly common practice: removing ETT deep to avoid coughing and desaturation, then inserting a laryngeal mask airway (LMA) which can be removed once the patient is awake in the postoperative care unit (PACU), avoiding the risk of airway obstruction coupled with deep airway removal. The aim of the study is to assess whether deep removal of an ETT and exchange to an LMA, is superior to awake ETT removal with regards to the occurrence of postoperative respiratory adverse events. In this study, patients will be randomised to awake removal of ETT or deep removal of an ETT and exchange to an LMA. Data will be collected regarding the rate of respiratory adverse events in either group, as well as the incidence of post-operative pain, delirium and nausea and vomiting.
Primary Outcome
Perioperative respiratory adverse events (PRAE) are defined as: Major PRAE: laryngospasm or bronchospasm, as determined by the anaesthetist, or desaturation \<85% SpO2 for more than 1 minute on pulse oximetry. Minor PRAE: desaturation (\<85% SpO2 for more than 10 secs on pulse oximetry), airway obstruction, severe coughing, post-operative stridor.
Interventions
- PROCEDURE Direct removal of endotracheal tube
- PROCEDURE Laryngeal mask airway inserted following deep extubation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,400 participants |
| Start Date | 2026-02-06 |
| Est. Completion | 2029-02-28 |
| Phase | NA |
What NCT07204990 shows while recruiting
NCT07204990 is an interventional study that assigns participants to a tested intervention. Its 1,400 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 1,404-participant average among 58,714 other NA trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Direct removal of endotracheal tube is the first listed.
NCT07204990 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07204990 about?
NCT07204990 is a clinical study titled "BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia". During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking up in (awake removal); or (2) the ETT is removed while still under anaes...
What is the current status of trial NCT07204990?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,400 participants. The study started on 2026-02-06. Estimated completion is 2029-02-28.
What interventions are being tested in trial NCT07204990?
The interventions under investigation include: Direct removal of endotracheal tube (PROCEDURE), Laryngeal mask airway inserted following deep extubation (PROCEDURE).
Who is sponsoring clinical trial NCT07204990?
This trial is sponsored by Telethon Kids Institute, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07204990's enrollment target sits among peer trials
1,400 71st of 2000 higher than 1,928 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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