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NCT07193875 · ClinicalTrials.gov registry record · Phase 4

Efavirenz (EFV) Intensification

A Phase 4 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 4
Development phase
7
Enrollment target

NCT07193875: Completed Phase 4 study, sponsored by Washington University School of Medicine.

NCT07193875 is a Phase 4 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 7 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07193875, a Phase 4 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 4
Development phase
7 participants
Enrollment target

Study Summary

The goal of this clinical trial is to see if Efavirenz (EFV) intensification to a baseline combination antiretroviral regimen (cART) can help reduce the size of the latent reservoir in people living with HIV (PLWH). The main questions this study aims to address are: 1. is the addition of EFV to a cART regimen safe and well tolerated? 2. Is there a reduction in the blood and tissue HIV reservoir after intensification? Researchers will compare each participants reservoir size prior to and post EFV intensification.

Primary Outcome

Safety as measured by number of serious adverse events, adverse events leading to study discontinuation or adverse events considered clinically significant

Interventions

  • DRUG Efavirenz 600mg

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2023-02-09
Est. Completion 2024-12-16
Phase Phase 4

What the finished NCT07193875 record still lists

NCT07193875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Efavirenz 600mg is the first listed.

NCT07193875 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07193875 about?

NCT07193875 is a clinical study titled "Efavirenz (EFV) Intensification". The goal of this clinical trial is to see if Efavirenz (EFV) intensification to a baseline combination antiretroviral regimen (cART) can help reduce the size of the latent reservoir in people living with HIV (PLWH). The main questions this study aims to address are: 1. is the addition of EFV to a c...

What is the current status of trial NCT07193875?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 7 participants. The study started on 2023-02-09. Estimated completion is 2024-12-16.

What interventions are being tested in trial NCT07193875?

The interventions under investigation include: Efavirenz 600mg (DRUG).

Who is sponsoring clinical trial NCT07193875?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07193875's enrollment target sits among peer trials

7 1981st of 2000 higher than 18 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07193875, the US trial registry maintained by the National Library of Medicine. NCT07193875 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.