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NCT07191327 · ClinicalTrials.gov registry record · NA
Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy
A NA study of Posterior Cortical Atrophy, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT07191327: Recruiting NA study of Posterior Cortical Atrophy, sponsored by University of Michigan.
NCT07191327 is a NA study of Posterior Cortical Atrophy that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07191327, a NA study of Posterior Cortical Atrophy, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA). Participants will be randomized to receive real or sham HD-tDCS (8 sessions over 4 days). Following the randomized treatment, participants will have optional open-label phase with real HD-tDCS up to 26 weeks and other possible testing.
Primary Outcome
Functional connectivity measures whether activity in different brain regions show similar patterns of change over time. Graph theory metrics of resting-state fMRI can characterize functional connectivity within the Dorsal Attention Network (DAN).
Conditions Studied
Interventions
- DEVICE HD-tDCS sessions
- DEVICE Sham HD-tDCS sessions
- DEVICE HD-tDCS sessions - Open-label (after randomized treatment)
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-01-28 |
| Est. Completion | 2029-09 |
| Phase | NA |
What NCT07191327 shows while recruiting
NCT07191327 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Posterior Cortical Atrophy appearing as the primary indexed condition, and to 3 interventions - of which HD-tDCS sessions is the first listed.
NCT07191327 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT07191327 about?
NCT07191327 is a clinical study titled "Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy". This study is being completed to learn if high-definition transcranial direct current stimulation (HD-tDCS) has an effect on visual and thinking abilities in persons with posterior cortical atrophy (PCA). Participants will be randomized to receive real or sham HD-tDCS (8 sessions over 4 days). Foll...
What is the current status of trial NCT07191327?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2026-01-28. Estimated completion is 2029-09.
What conditions does trial NCT07191327 study?
This clinical trial studies the following conditions: Posterior Cortical Atrophy.
What interventions are being tested in trial NCT07191327?
The interventions under investigation include: HD-tDCS sessions (DEVICE), Sham HD-tDCS sessions (DEVICE), HD-tDCS sessions - Open-label (after randomized treatment) (DEVICE).
Who is sponsoring clinical trial NCT07191327?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07191327 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07191327's enrollment target sits among peer trials
50 1280th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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