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NCT07190352 · ClinicalTrials.gov registry record · NA

Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia

A NA study, sponsored by Vanderbilt University Medical Center.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT07190352: Completed NA study, sponsored by Vanderbilt University Medical Center.

NCT07190352 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07190352, a NA study, has completed, sponsored by Vanderbilt University Medical Center.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

The primary aims of this study are to investigate the behavioral effects of applying targeted transcranial magnetic stimulation (TMS) to a node of the brain network subserving attention in schizophrenia and schizoaffective disorder and to correlate these effects to changes in brain network connectivity. Assumptions: -Cerebral activity can be investigated through the correlated activity of cortical nodes that constitute functional brain networks -Behavior can be correlated to the strength of correlated activity between and within nodes of these cortical networks -TMS to targeted nodes leads to changes in patterns of activity in these cortical networks Hypothesis: TMS to a node of the attention network in schizophrenia or schizoaffective disorder will influence network connectivity leading to measurable and predictable effects on attention.

Primary Outcome

Nicotine craving is assessed using 0-10 Visual Analog Scale (VAS) immediately before and after rTMS application. The VAS ranges from 0 to 10, where 0 indicates "no craving," and higher numbers indicate more craving.

Interventions

  • DEVICE Sham rTMS
  • DEVICE iTBS to the DMN
  • DEVICE cTBS to the DMN

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2021-10-04
Est. Completion 2022-10-03
Phase NA

What the finished NCT07190352 record still lists

NCT07190352 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which Sham rTMS is the first listed.

NCT07190352 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07190352 about?

NCT07190352 is a clinical study titled "Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia". The primary aims of this study are to investigate the behavioral effects of applying targeted transcranial magnetic stimulation (TMS) to a node of the brain network subserving attention in schizophrenia and schizoaffective disorder and to correlate these effects to changes in brain network connectiv...

What is the current status of trial NCT07190352?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2021-10-04. Estimated completion is 2022-10-03.

What interventions are being tested in trial NCT07190352?

The interventions under investigation include: Sham rTMS (DEVICE), iTBS to the DMN (DEVICE), cTBS to the DMN (DEVICE).

Who is sponsoring clinical trial NCT07190352?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07190352's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07190352, the US trial registry maintained by the National Library of Medicine. NCT07190352 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.