Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
NCT07190209 · View on ClinicalTrials.gov ↗
Study Summary
This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. Participation to the study consists of 3 periods: * Screening period of up to 4 weeks * Randomized intervention period of approximately 48 weeks * Follow-up period: Approximately 8 weeks The study duration will be up to 60 weeks.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Lunsekimig
Study Locations (20)
Florida
- Helix Biomedics- Site Number : 8400065 — Boynton Beach
- Beautiful Minds Clinical Research Center- Site Number : 8400017 — Cutler Bay
- Eastern Medical Group Research- Site Number : 8400020 — Fort Myers
- Premier Medical Associates- Site Number : 8400012 — Lady Lake
- MCR Research- Site Number : 8400004 — Miami
- Nuren Medical & Research Center- Site Number : 8400030 — Miami
- Deluxe Health Center- Site Number : 8400010 — Miami Lakes
- Omega Research Consultants - Orlando - Forest City- Site Number : 8400015 — Orlando
- Broward Research Center - Pembroke Pines- Site Number : 8400053 — Pembroke Pines
- Clinical Research Trials of Florida- Site Number : 8400011 — Tampa
- Deluxe Health Center-Tampa- Site Number : 8400056 — Tampa
California
- IMAX Clinical Trials- Site Number : 8400109 — La Palma
- Long Beach Research Institute- Site Number : 8400027 — Long Beach
- Downtown L.A. Research Center- Site Number : 8400009 — Los Angeles
- Newport Native MD- Site Number : 8400003 — Newport Beach
- Paradigm Research - Redding- Site Number : 8400108 — Redding
- Amicis Research Center - Valencia- Site Number : 8400119 — Valencia
Arizona
- Chandler Clinical Research Trials- Site Number : 8400025 — Chandler
- Pulmonary Associates - Phoenix - East Bell Road- Site Number : 8400114 — Phoenix
- Epic Medical Research - Surprise- Site Number : 8400096 — Surprise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 942 participants |
| Start Date | 2025-09-16 |
| Est. Completion | 2030-01-22 |
| Phase | Phase 3 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07190209
The ClinicalTrials.gov registry entry for NCT07190209 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 942 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 275 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07190209 reports 20 study locations spanning 3 distinct geographic areas — top geographies include Florida, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07190209 about?
NCT07190209 is a clinical study titled "Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype". This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD...
What is the current status of trial NCT07190209?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 942 participants. The study started on 2025-09-16. Estimated completion is 2030-01-22.
What conditions does trial NCT07190209 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07190209?
The interventions under investigation include: Placebo (DRUG), Lunsekimig (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07190209?
This trial is sponsored by Sanofi, which has 275 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07190209 being conducted?
This trial has 20 study locations across Arizona, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.