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NCT07173777 · ClinicalTrials.gov registry record · NA
Cardiac Anodal Biphasic Pacing
A NA study, sponsored by Boston Medical Center.
- Not yet
- Registry status
- NA
- Development phase
- 108
- Enrollment target
NCT07173777: Clinical Trial NA study, sponsored by Boston Medical Center.
NCT07173777 is a NA study that has not yet begun recruiting, run by Boston Medical Center. The registered enrollment target is 108 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07173777, a NA study, has not yet begun recruiting, sponsored by Boston Medical Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 108 participants
- Enrollment target
Study Summary
The goal of this study is to test a new pacing method called anodal biphasic pacing (ABP) to determine if this pacing works as well-or better-than current pacing methods. This new method may improve how the heart works and reduce some of the problems caused by regular pacing. Current implantable pacemakers use a monophasic cathodal waveform to stimulate the heart. Monophasic cathodal pacing (MCP) waveforms slow conduction, impair contractility, cause inflammation, increase risk of atrial fibrillation, heart failure, and mortality. Anodal biphasic pacing (ABP) is an alternative waveform that can stimulate the heart. ABP preconditions the heart and then initiates cardiac contraction. ABP may address the limitations of MCP.
Primary Outcome
Response will be expressed as a percent change in these measures with anodal biphasic pacing (ABP) as compared with cathodal pacing. A clinically significant hemodynamic response to pacing will be defined as a \>10% increase in dP/dtmax.
Interventions
- DEVICE Cardiac Waveform Generator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2026-07 |
| Est. Completion | 2027-07 |
| Phase | NA |
What is known before NCT07173777 opens enrollment
NCT07173777 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Cardiac Waveform Generator is the first listed.
NCT07173777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07173777 about?
NCT07173777 is a clinical study titled "Cardiac Anodal Biphasic Pacing". The goal of this study is to test a new pacing method called anodal biphasic pacing (ABP) to determine if this pacing works as well-or better-than current pacing methods. This new method may improve how the heart works and reduce some of the problems caused by regular pacing. Current implantable pa...
What is the current status of trial NCT07173777?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 108 participants. The study started on 2026-07. Estimated completion is 2027-07.
What interventions are being tested in trial NCT07173777?
The interventions under investigation include: Cardiac Waveform Generator (DEVICE).
Who is sponsoring clinical trial NCT07173777?
This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07173777's enrollment target sits among peer trials
108 825th of 2000 higher than 1,171 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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