Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07164469 · ClinicalTrials.gov registry record · Phase 2

Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Not yet
Registry status
Phase 2
Development phase
100
Enrollment target

NCT07164469: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT07164469 is a Phase 2 study that has not yet begun recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT07164469, a Phase 2 study, has not yet begun recruiting, sponsored by M.D. Anderson Cancer Center.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target

Study Summary

This clinical research study is to learn if CD70.CAR NK cell therapy can help to control early relapsed or primary refractory DLBCL and cHL.

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine
  • DRUG Rimiducid (AP1903)
  • DRUG CD70.CAR NK Cells

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2026-06-28
Est. Completion 2033-09-30
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What is known before NCT07164469 opens enrollment

NCT07164469 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).

The record links to 0 conditions, and to 4 interventions - of which Cyclophosphamide is the first listed.

NCT07164469 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07164469 about?

NCT07164469 is a clinical study titled "Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma". This clinical research study is to learn if CD70.CAR NK cell therapy can help to control early relapsed or primary refractory DLBCL and cHL.

What is the current status of trial NCT07164469?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2026-06-28. Estimated completion is 2033-09-30.

What interventions are being tested in trial NCT07164469?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), Rimiducid (AP1903) (DRUG), CD70.CAR NK Cells (DRUG).

Who is sponsoring clinical trial NCT07164469?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07164469's enrollment target sits among peer trials

100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01048281 · 100 participants

    Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  • NCT01161199 · 100 participants

    The Use of Leukapheresis to Support HIV Pathogenesis Studies

  • NCT01327690 · 100 participants · Early Phase 1

    Mental Health in Veterans and Families After Group Therapies

  • NCT01730781 · 100 participants

    Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07164469, the US trial registry maintained by the National Library of Medicine. NCT07164469 (mid enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.