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NCT07154719 · ClinicalTrials.gov registry record · Phase 4
GLP-1R Actions on Muscle and the Skeleton
A Phase 4 study, sponsored by Pennington Biomedical Research Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 50
- Enrollment target
NCT07154719: Recruiting Phase 4 study, sponsored by Pennington Biomedical Research Center.
NCT07154719 is a Phase 4 study that is actively recruiting participants, run by Pennington Biomedical Research Center. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07154719, a Phase 4 study, is actively recruiting participants, sponsored by Pennington Biomedical Research Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 50 participants
- Enrollment target
Study Summary
The GRAMS study objectives are to assess the musculoskeletal changes that occur after weight loss using GLP-1 based therapy. A lifestyle intervention with diet and exercise is included to assess any mitigating effects are provided, versus a control group with regular exercise and diet.
Primary Outcome
DXA (Dual energy Xray absorptiometry)
Interventions
- DRUG Tirzepatide
- BEHAVIORAL Lifestyle toolkit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-10-09 |
| Est. Completion | 2027-05-01 |
| Phase | Phase 4 |
What NCT07154719 shows while recruiting
NCT07154719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Tirzepatide is the first listed.
NCT07154719 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07154719 about?
NCT07154719 is a clinical study titled "GLP-1R Actions on Muscle and the Skeleton". The GRAMS study objectives are to assess the musculoskeletal changes that occur after weight loss using GLP-1 based therapy. A lifestyle intervention with diet and exercise is included to assess any mitigating effects are provided, versus a control group with regular exercise and diet.
What is the current status of trial NCT07154719?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2025-10-09. Estimated completion is 2027-05-01.
What interventions are being tested in trial NCT07154719?
The interventions under investigation include: Tirzepatide (DRUG), Lifestyle toolkit (BEHAVIORAL).
Who is sponsoring clinical trial NCT07154719?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07154719's enrollment target sits among peer trials
50 1255th of 2000 higher than 678 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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