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NCT07135401 · ClinicalTrials.gov registry record · NA

Optimizing Liver MRI Using Breath-Holding With and Without Oxygen

A NA study, sponsored by University of California, San Francisco.

Recruiting
Registry status
NA
Development phase
10
Enrollment target

NCT07135401: Recruiting NA study, sponsored by University of California, San Francisco.

NCT07135401 is a NA study that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07135401, a NA study, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75. The main questions it aims to answer are: * Does breath-holding at end-expiration improve image quality in abdominal MRI scans? * Does adding oxygen while breath-holding further reduce motion artifacts in abdominal MRI scans? Researchers will compare breath-holding with and without oxygen to see if using oxygen improves image quality during MRI scans. Participants will: * Be pre-screened for MRI safety and trained on breath-hold procedures * Have one non-contrast abdominal MRI scan at the University of California San Francisco (UCSF) China Basin Imaging Center * Use two different breath-holding techniques during the scan, with and without oxygen * Complete one study visit lasting about 45 minutes to 1 hour

Primary Outcome

Image quality of liver MRI scans will be assessed by quantifying the degree of respiratory motion artifacts under two breath-holding conditions: Functional Residual Capacity (FRC) alone and FRC with oxygen supplementation. Reduced artifacts indicate improved image clarity and feasibility of the technique. Unit of Measure: Motion artifact score (ordinal scale, e.g., 1-5).

Interventions

  • OTHER Breath-hold conditions

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-12-01
Est. Completion 2026-08-01
Phase NA

What NCT07135401 shows while recruiting

NCT07135401 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Breath-hold conditions is the first listed.

NCT07135401 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07135401 about?

NCT07135401 is a clinical study titled "Optimizing Liver MRI Using Breath-Holding With and Without Oxygen". The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75. The main questions it aims to answer are: * Does bre...

What is the current status of trial NCT07135401?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-12-01. Estimated completion is 2026-08-01.

What interventions are being tested in trial NCT07135401?

The interventions under investigation include: Breath-hold conditions (OTHER).

Who is sponsoring clinical trial NCT07135401?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07135401's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07135401, the US trial registry maintained by the National Library of Medicine. NCT07135401 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.