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NCT07132918 · ClinicalTrials.gov registry record · Phase 2

HEARTS Trial for Thoracic Cancers

A Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III, sponsored by University of Wisconsin, Madison.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
1
Study location

NCT07132918 is a Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 60 participants, below the 93-participant average among 6 other Non-Small Cell Lung Cancer (Stage III) trials with a reported enrollment target (35% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07132918, a Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III, is actively recruiting participants, sponsored by University of Wisconsin, Madison.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether MRgART affects the heart differently than LINAC. Participants will: * Receive radiation therapy * Undergo MRIs and bloodwork * Complete quality of life questionnaires

Conditions Studied

Non-Small Cell Lung Cancer (Stage III) Esophageal Cancer Stage I-III Esophagogastric Cancer Stage I-III Thymoma and Thymic Carcinoma Stage II-III Other Cancers in the Thoracic Region

Interventions

  • RADIATION MRgART
  • RADIATION LINAC

Study Locations (1)

Wisconsin

  • University of Wisconsin - Madison - Madison

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-10-08
Est. Completion 2029-03
Phase Phase 2

Sponsor

University of Wisconsin, Madison

1,039 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07132918

The ClinicalTrials.gov registry entry for NCT07132918 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 93-participant average among 6 other Non-Small Cell Lung Cancer (Stage III) trials with a reported enrollment target (35% lower). The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Non-Small Cell Lung Cancer (Stage III) appearing as the primary indexed condition, and to 2 interventions - of which MRgART is the first listed.

NCT07132918 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT07132918 about?

NCT07132918 is a clinical study titled "HEARTS Trial for Thoracic Cancers". The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is w...

What is the current status of trial NCT07132918?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-10-08. Estimated completion is 2029-03.

What conditions does trial NCT07132918 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer (Stage III), Esophageal Cancer Stage I-III, Esophagogastric Cancer Stage I-III, Thymoma and Thymic Carcinoma Stage II-III, Other Cancers in the Thoracic Region.

What interventions are being tested in trial NCT07132918?

The interventions under investigation include: MRgART (RADIATION), LINAC (RADIATION).

Who is sponsoring clinical trial NCT07132918?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07132918 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.