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NCT07132918 · ClinicalTrials.gov registry record · Phase 2
HEARTS Trial for Thoracic Cancers
A Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III, sponsored by University of Wisconsin, Madison.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT07132918: Recruiting Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III, sponsored by University of Wisconsin, Madison.
NCT07132918 is a Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 60 participants, below the 81-participant average among 8 other Non-Small Cell Lung Cancer (Stage III) trials with a reported enrollment target (26% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07132918, a Phase 2 study of Non-Small Cell Lung Cancer (Stage III) and Esophageal Cancer Stage I-III, is actively recruiting participants, sponsored by University of Wisconsin, Madison.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether MRgART affects the heart differently than LINAC. Participants will: * Receive radiation therapy * Undergo MRIs and bloodwork * Complete quality of life questionnaires
Primary Outcome
Changes are measured between timepoints as determined by cardiac MRI. LVEF is calculated by dividing the left ventricular (LV) stroke volume (the amount of blood pumped out) by the end-diastolic volume (the amount of blood in the left ventricle before contraction) and multiplying by 100.
Conditions Studied
Interventions
- RADIATION MRgART
- RADIATION LINAC
Study Locations (1)
Wisconsin
- University of Wisconsin - Madison - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-10-08 |
| Est. Completion | 2029-03 |
| Phase | Phase 2 |
What NCT07132918 shows while recruiting
NCT07132918 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 81-participant average among 8 other Non-Small Cell Lung Cancer (Stage III) trials with a reported enrollment target (26% lower).
The record links to 5 conditions, with Non-Small Cell Lung Cancer (Stage III) appearing as the primary indexed condition, and to 2 interventions - of which MRgART is the first listed.
NCT07132918 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT07132918 about?
NCT07132918 is a clinical study titled "HEARTS Trial for Thoracic Cancers". The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is w...
What is the current status of trial NCT07132918?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-10-08. Estimated completion is 2029-03.
What conditions does trial NCT07132918 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer (Stage III), Esophageal Cancer Stage I-III, Esophagogastric Cancer Stage I-III, Thymoma and Thymic Carcinoma Stage II-III, Other Cancers in the Thoracic Region.
What interventions are being tested in trial NCT07132918?
The interventions under investigation include: MRgART (RADIATION), LINAC (RADIATION).
Who is sponsoring clinical trial NCT07132918?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07132918 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Small Cell Lung Cancer (Stage III)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07132918's enrollment target sits among peer trials
60 5th of 8 higher than 3 of 8 other Non-Small Cell Lung Cancer (Stage III) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Small Cell Lung Cancer (Stage III) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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