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NCT07131384 · ClinicalTrials.gov registry record · NA
Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes
A NA study, sponsored by University of Virginia.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT07131384: Recruiting NA study, sponsored by University of Virginia.
NCT07131384 is a NA study that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07131384, a NA study, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study is examining whether short-term supplementation with inorganic nitrate, in the form of beetroot juice, can enhance blood vessel health, insulin sensitivity, and exercise capacity in individuals with prediabetes. We will be comparing the responses in individuals who are taking metformin to those who are naive to metformin. The results from this study may help identify non-pharmacological interventions in prediabetes.
Primary Outcome
PWA/V- These measures will be calculated using the SphygmoCor XCEL system (AtCor Medical). This system will provide arterial stiffness, central, and peripheral pressure waveforms.
Interventions
- DIETARY_SUPPLEMENT Dietary Supplement: Inorganic Nitrate (Beetroot juice)
- DIETARY_SUPPLEMENT Dietary supplement: Placebo (Nitrate-depleted beetroot juice)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT07131384 shows while recruiting
NCT07131384 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Dietary Supplement: Inorganic Nitrate (Beetroot juice) is the first listed.
NCT07131384 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07131384 about?
NCT07131384 is a clinical study titled "Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes". This study is examining whether short-term supplementation with inorganic nitrate, in the form of beetroot juice, can enhance blood vessel health, insulin sensitivity, and exercise capacity in individuals with prediabetes. We will be comparing the responses in individuals who are taking metformin to...
What is the current status of trial NCT07131384?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2026-01-01. Estimated completion is 2027-06-30.
What interventions are being tested in trial NCT07131384?
The interventions under investigation include: Dietary Supplement: Inorganic Nitrate (Beetroot juice) (DIETARY_SUPPLEMENT), Dietary supplement: Placebo (Nitrate-depleted beetroot juice) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07131384?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07131384's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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