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NCT07122739 · ClinicalTrials.gov registry record · NA
Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy
A NA study of Healthy, sponsored by Trustees of Princeton University.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07122739: Recruiting NA study of Healthy, sponsored by Trustees of Princeton University.
NCT07122739 is a NA study of Healthy that is actively recruiting participants, run by Trustees of Princeton University. The registered enrollment target is 40 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07122739, a NA study of Healthy, is actively recruiting participants, sponsored by Trustees of Princeton University.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.
Primary Outcome
The investigators will assess neurofeedback related changes in behavioral threat expectancy ratings in a discriminatory Pavlovian conditioning task. Spontaneous recovery is taken as the difference in responding to the conditioned stimulus that was paired with an outcome (CS+) vs. the conditioned stimulus that was not paired with an outcome (CS-) during a test of extinction recall following acquisition and extinction learning.
Conditions Studied
Interventions
- BEHAVIORAL Active Real-time fMRI Neurofeedback
- BEHAVIORAL Sham Real-time fMRI neurofeedback
Study Locations (1)
New Jersey
- Princeton Neuroscience Institute - Princeton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-07-17 |
| Est. Completion | 2028-06 |
| Phase | NA |
What NCT07122739 shows while recruiting
NCT07122739 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Active Real-time fMRI Neurofeedback is the first listed.
NCT07122739 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT07122739 about?
NCT07122739 is a clinical study titled "Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy". This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the ...
What is the current status of trial NCT07122739?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-07-17. Estimated completion is 2028-06.
What conditions does trial NCT07122739 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT07122739?
The interventions under investigation include: Active Real-time fMRI Neurofeedback (BEHAVIORAL), Sham Real-time fMRI neurofeedback (BEHAVIORAL).
Who is sponsoring clinical trial NCT07122739?
This trial is sponsored by Trustees of Princeton University, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07122739 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07122739's enrollment target sits among peer trials
40 540th of 1090 higher than 513 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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