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NCT07116499 · ClinicalTrials.gov registry record · Phase 2
A Study of K-645 in the Treatment of Multiple Migraine Attacks
A Phase 2 study, sponsored by Kallyope.
- Terminated
- Registry status
- Phase 2
- Development phase
- 134
- Enrollment target
NCT07116499: Clinical Trial Phase 2 study, sponsored by Kallyope.
NCT07116499 is a Phase 2 study that was terminated before completion, run by Kallyope. The registered enrollment target is 134 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07116499, a Phase 2 study, was terminated before completion, sponsored by Kallyope.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 134 participants
- Enrollment target
Study Summary
This is a multicenter, randomized, double-blind, placebo-controlled, 3-period crossover study to evaluate the safety, tolerability, and efficacy of two dose levels of K-645 in the treatment of patients with acute migraine.
Interventions
- DRUG Placebo
- DRUG K-645 dose level 1
- DRUG K-645 dose level 2
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2025-08-12 |
| Est. Completion | 2025-11-07 |
| Phase | Phase 2 |
Why NCT07116499 stopped before completion
NCT07116499 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT07116499 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07116499 about?
NCT07116499 is a clinical study titled "A Study of K-645 in the Treatment of Multiple Migraine Attacks". This is a multicenter, randomized, double-blind, placebo-controlled, 3-period crossover study to evaluate the safety, tolerability, and efficacy of two dose levels of K-645 in the treatment of patients with acute migraine.
What is the current status of trial NCT07116499?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 134 participants. The study started on 2025-08-12. Estimated completion is 2025-11-07.
What interventions are being tested in trial NCT07116499?
The interventions under investigation include: Placebo (DRUG), K-645 dose level 1 (DRUG), K-645 dose level 2 (DRUG).
Who is sponsoring clinical trial NCT07116499?
This trial is sponsored by Kallyope, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07116499's enrollment target sits among peer trials
134 537th of 2000 higher than 1,463 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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